MRI findings of serous atrophy of bone marrow and associated complications

European Radiology
Robert D BoutinMiriam A Bredella

Abstract

To report the MRI appearance of serous atrophy of bone marrow (SABM) and analyse clinical findings and complications of SABM. A retrospective search of MRI examinations of SABM was performed. Symptoms, underlying conditions, MRI findings, delay in diagnosis and associated complications were recorded. We identified 30 patients (15 male, 15 female; mean age: 46 ± 21 years) with MRI findings of SABM. Underlying conditions included anorexia nervosa (n = 10), cachexia from malignant (n = 5) and non-malignant (n = 7) causes, massive weight loss after bariatric surgery (n = 1), biliary atresia (n = 1), AIDS (n = 3), endocrine disorders (n = 2) and scurvy (n = 1). MRI showed mildly hypointense signal on T1- weighted and hyperintense signal on fat-suppressed fluid-sensitive images of affected bone marrow in all cases and similar signal abnormalities of the adjacent subcutaneous fat in 29/30 cases. Seven patients underwent repeat MRI due to initial misinterpretation of bone marrow signal as technical error. Superimposed fractures of the hips and lower extremities were common (n = 14). SABM occurs most commonly in anorexia nervosa and cachexia. MRI findings of SABM are often misinterpreted as technical error requiring unnecessary repeat i...Continue Reading

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Oct 4, 2016·Frontiers in Endocrinology·Olfa GhaliChristophe Chauveau
Jun 4, 2020·Skeletal Radiology·William PalmerChristian W A Pfirrmann
Feb 15, 2020·Insights Into Imaging·Asako YamamotoHiroshi Oba
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Aug 22, 2020·The British Journal of Radiology·Nina TunariuDow-Mu Koh
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Mar 3, 2021·Best Practice & Research. Clinical Endocrinology & Metabolism·Mohamed Jarraya, Miriam A Bredella
Oct 3, 2021·BMJ Case Reports·Vilim KalamarPriya Suresh

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