MRI-guided frameless biopsy robotic system with the inclusion of unfocused ultrasound transducer for brain cancer ablation

The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS
Marinos GiannakouChristakis Damianou

Abstract

A magnetic resonance image (MRI) guided robotic system dedicated for brain biopsy was developed. The robotic system carries a biopsy needle and a small rectangular unfocused, single element, planar ultrasonic transducer which can be potentially utilized to ablate small and localized brain cancer. The robotic device includes six computer-controlled axes. An agar-based phantom was developed which included an olive that mimics brain target. A rectangular ultrasonic transducer operated at 4 MHz was used. The functionality of the robotic system was assessed by means of ultrasound imaging, MRI imaging, and MR thermometry, demonstrating effective targeting. The heating capabilities of the ultrasonic transducer were also evaluated. A functional MRI-guided robotic system was produced which can perform frameless brain biopsy. In the future, if a tumour is proven malignant, the needle can be pulled-out and a small ultrasonic transducer can be inserted to ablate the tumour.

References

Aug 1, 1995·Journal of Neurosurgery·J G GolfinosR F Spetzler
Jan 1, 1997·Stereotactic and Functional Neurosurgery·O AlbertiD G Thomas
Jun 6, 2002·British Journal of Neurosurgery·N L DorwardD G T Thomas
Sep 1, 2005·Oral Oncology·Julia Anne Woolgar, Asterios Triantafyllou
Oct 10, 1947·Science·E A SpiegelA J Lee
Jan 26, 2008·Journal of Magnetic Resonance Imaging : JMRI·Clifford R WeissJonathan S Lewin
Jul 30, 2008·Stereotactic and Functional Neurosurgery·L Dade LunsfordDouglas Kondziolka
Nov 19, 2011·Prostate Cancer·Kenneth A IczkowskiM Scott Lucia
Aug 1, 2012·Acta neurochirurgica·Jens GemptFlorian Ringel
Jun 8, 2013·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·N Mylonas, C Damianou
Aug 16, 2013·The New England Journal of Medicine·W Jeffrey EliasMax Wintermark
Oct 15, 2013·BJU International·Govindarajan SrimathveeravalliDan Stoianovici
Dec 18, 2013·International Journal of Computer Assisted Radiology and Surgery·Christos YiallourasChristakis Damianou
Nov 7, 2014·IEEE Transactions on Bio-medical Engineering·Gang LiGregory Fischer
Dec 9, 2014·Ultrasonics·Georgios MenikouChristakis Damianou
Mar 27, 2015·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Eva EpaminondaChristakis Damianou
Jun 5, 2016·Ultrasonics·Georgios MenikouChristakis Damianou
Jul 13, 2016·The International Journal of Medical Robotics + Computer Assisted Surgery : MRCAS·Kathryn G ChanMehran Anvari

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Citations

May 30, 2021·Operative Neurosurgery·Christopher R WagnerJoseph P Corrigan

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