MRI identification of dorsal hippocampus homologue in human brain

Neuroreport
Makoto SasakiAkira Ogawa

Abstract

We investigated hippocampal substructure in the rat, cat, dog, and human by means of magnetic resonance imaging to elucidate phylogenetic differences in longitudinal organization. Multidirectional high-resolution images obtained with a 3 T scanner revealed that the dorsal part of the hippocampus was well developed in the rat, cat, and dog brain, and was homologous to the hippocampal tail, a poorly-developed posterior part, in the human. We conclude that the dorsal hippocampus of laboratory animals corresponds to the hippocampal tail in the human brain, which is considered to be hypoplastic and of less importance clinically than more anterior regions. These data may help in understanding phylogenetic, and in correlating results from animal experiments with clinical findings on the functions and pathologies of the human hippocampus.

References

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Citations

Aug 16, 2008·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Lara G ChepenikHilary P Blumberg
Apr 16, 2010·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Bryon AdinoffMunro Cullum
May 16, 2013·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Ashley C Chen, Amit Etkin
Dec 14, 2006·Neuroreport·Philip R SzeszkoRobert M Bilder
Dec 3, 2014·Trends in Pharmacological Sciences·Olivia F O'Leary, John F Cryan
Apr 24, 2009·Journal of Magnetic Resonance Imaging : JMRI·R Edward HoganTerence J O'Brien
Apr 5, 2014·Brain Pathology·Eva WagnerKaspar Matiasek
Mar 10, 2015·Biological Psychiatry·Bryon AdinoffElliot A Stein
Mar 18, 2015·Neuroscience Letters·Aileen LoweMichael Valenzuela
May 3, 2014·The International Journal of Neuropsychopharmacology·Kathryn M Gill, Anthony A Grace
Jul 23, 2008·Neurobiology of Learning and Memory·V Hernández-RabazaJ J Canales
May 8, 2018·Harvard Review of Psychiatry·Philip R SzeszkoRachel Yehuda
Feb 22, 2018·American Journal of Veterinary Research·Yoshihiko YuKazuyuki Uchida
Aug 14, 2018·NeuroImage. Clinical·Paul M MaceyRonald M Harper

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