MRI measurements of intracranial pressure in the upright posture: The effect of the hydrostatic pressure gradient

Journal of Magnetic Resonance Imaging : JMRI
N AlperinAhmet M Bagci

Abstract

To add the hydrostatic component of the cerebrospinal fluid (CSF) pressure to magnetic resonance imaging (MRI)-derived intracranial pressure (ICP) measurements in the upright posture for derivation of pressure value in a central cranial location often used in invasive ICP measurements. Additional analyses were performed using data previously collected from 10 healthy subjects scanned in supine and sitting positions with a 0.5T vertical gap MRI scanner (GE Medical). Pulsatile blood and CSF flows to and from the brain were quantified using cine phase-contrast. Intracranial compliance and pressure were calculated using a previously described method. The vertical distance between the location of the CSF flow measurement and a central cranial location was measured manually in the mid-sagittal T1 -weighted image obtained in the upright posture. The hydrostatic pressure gradient of a CSF column with similar height was then added to the MR-ICP value. After adjustment for the hydrostatic component, the mean ICP value was reduced by 7.6 mmHg. Mean ICP referenced to the central cranial level was -3.4 ± 1.7 mmHg compared to the unadjusted value of +4.3 ± 1.8 mmHg. In the upright posture, the hydrostatic pressure component needs to be added...Continue Reading

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Citations

Jun 4, 2017·Journal of Magnetic Resonance Imaging : JMRI·Shota IshidaToshifumi Gabata
Aug 10, 2017·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·V R BollelaS Mascarenhas
Nov 10, 2017·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·P HolmlundS Qvarlander
Nov 11, 2019·The British Journal of Ophthalmology·David Andrew PriceAlon Harris
Jan 26, 2021·Journal of Magnetic Resonance Imaging : JMRI·Noam AlperinSang H Lee
Jan 13, 2021·Scientific Reports·Yoichi YokoyamaMasahiro Jinzaki
Jun 12, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·U W Thomale
Dec 26, 2021·Fluids and Barriers of the CNS·Marco MuccioYulin Ge

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