PMID: 8957807Nov 1, 1996Paper

MRI of adrenoleukodystrophy involving predominantly the cerebellum and brain stem

Neuroradiology
M WaragaiM Kobayashi

Abstract

A case of adult-onset adrenoleukodystrophy involving predominantly the cerebellum and brain stem is described. The patient was a 30-year-old man with no family history of adrenoleukodystrophy. His neurological symptoms were progressive cerebellar ataxia and spastic paraparesis. CT showed atrophy of the cerebellum and brain stem. MRI disclosed lesions, enhancing partially with gadolinium, in the dentate nuclei and the pyramidal tracts from the internal capsule to the brain stem. The biochemical findings were compatible with typical adrenoleukodystrophy, but the distribution of the lesions on MRI was distinctly different. After steroid administration, the patient's symptoms improved slightly and contrast enhancement of the lesions was markedly reduced.

Citations

Sep 1, 1999·Clinical Neurology and Neurosurgery·E K TanK P Tan
Sep 15, 2006·Journal of the Chinese Medical Association : JCMA·Shuang WangYuan-Shen Cheng
Apr 11, 2007·Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine·Shoji Tsuji
Oct 1, 2009·Journal of Movement Disorders·Seunguk JungBeom Seok Jeon
Aug 1, 2015·Neuropathology : Official Journal of the Japanese Society of Neuropathology·Kotaro OgakiDennis W Dickson
Dec 21, 2007·Journal of Neuroradiology. Journal De Neuroradiologie·F HerissonH Desal
Apr 11, 2014·Yonsei Medical Journal·Hyung Jun ParkSeung Min Kim
Aug 23, 2005·Transactions of the Royal Society of Tropical Medicine and Hygiene·Rajeev M KaushikRanjan Kukreti

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