MRI pattern approach of adult-onset inherited leukoencephalopathies

Neurology. Clinical Practice
Pierre LabaugeOdile Boespflug-Tanguy

Abstract

White matter hyperintensities are frequently encountered in clinical practice. In adulthood, white matter hyperintensities are generally related to acquired disorders, such as vascular, inflammatory, or demyelinating diseases. Symmetrical and confluent white matter abnormalities on the first available MRI suggest a genetic disorder. In this article, we provide keys to recognize and classify the adult-onset forms of inherited leukoencephalopathies and to identify their causes by targeting specific biochemical or molecular biomarkers.

Citations

Apr 30, 2016·Journal of Neurology·Xavier AyrignacPierre Labauge
Apr 1, 2016·Neurology. Clinical Practice·Joel C Morgenlander
Dec 21, 2014·Brain : a Journal of Neurology·Xavier AyrignacPierre Labauge
Jun 6, 2020·Neurology. Neuroimmunology and Neuroinflammation·Xavier AyrignacPhilippe Guilpain
Sep 21, 2021·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·Xavier AyrignacPierre Labauge

❮ Previous
Next ❯

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Related Papers

BMJ : British Medical Journal
Anders Wallin, Tormod Fladby
BMJ : British Medical Journal
Joe J Vattakatuchery, Jaya Joy
Journal of the American Academy of Child and Adolescent Psychiatry
I K LyooH K Lee
Seminars in Neurology
Deborah L Renaud
© 2022 Meta ULC. All rights reserved