MRI to differentiate benign from malignant soft-tissue tumours of the extremities: a simplified systematic imaging approach using depth, size and heterogeneity of signal intensity.

The British Journal of Radiology
W J ChungW K Lee

Abstract

Differentiating between malignant and benign lesions on the basis of MR images depends on the experience of the radiologist. For non-experts, we aimed to develop a simplified systematic MRI approach that uses depth, size and heterogeneity on T(2) weighted MR images (T(2)WI) to differentiate between malignant and benign lesions, and evaluated its diagnostic accuracy. MR images of 266 patients with histologically proven soft-tissue tumours of the extremities (102 malignant, 164 benign) were analysed according to depth (superficial or deep), size (<50, ≥50 mm) and signal intensity (homogeneous or heterogeneous) on T(2)WI, to determine the ability of each to predict benign and malignant tumours. These three parameters were categorised into systematic combinations of different orders of application, and each combination was assessed for its ability to differentiate between benign and malignant lesions. Univariate analysis showed that depth, size and heterogeneity on T(2)WI differed significantly between benign and malignant masses (p<0.0001 each). Multiple logistic regression analysis, however, showed that depth was not helpful in distinguishing benign from malignant lesions. The systematic combination of signal intensity, size and ...Continue Reading

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Citations

Feb 10, 2016·The Journal of Hand Surgery·Mohammad M Al-Qattan
Mar 11, 2016·European Radiology·Leonhard GruberHannes Gruber
Nov 6, 2015·Indian Journal of Dermatology·K Nagarajan, C S Banushree
Apr 15, 2015·Ultrasonography·Hye Won Chung, Kil-Ho Cho
Dec 14, 2016·AJR. American Journal of Roentgenology·Leonhard GruberHannes Gruber
May 20, 2014·Insights Into Imaging·Chau Hung Lee, Ankit Tandon
Dec 28, 2018·AJR. American Journal of Roentgenology·Chris L ScelsiBruce C Gilbert
May 20, 2018·BMC Musculoskeletal Disorders·Jessica RauhHans Roland Dürr
Jun 7, 2019·Journal of Magnetic Resonance Imaging : JMRI·Hexiang WangJihua Liu
May 28, 2019·Current Treatment Options in Oncology·Makoto EndoYoshihiro Matsumoto
May 16, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·Greydon GilmoreMandar Jog
Mar 8, 2021·European Journal of Radiology·Teodoro Martín-NoguerolAntonio Luna

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