MRI volumetry shows increased anterior thalamic volumes in patients with absence seizures

Epilepsy & Behavior : E&B
Luiz Eduardo BettingFernando Cendes

Abstract

The interaction between thalamus and cortex appears to be critical to the pathophysiology of idiopathic generalized epilepsies (IGEs). The objective of this study was to investigate thalamic volumes of a group of patients with IGEs using high-resolution MRI. Thalamic segmentation was performed by the same rater, who was unaware of the diagnosis. Thalamic volumes were divided into anterior half and posterior half. One hundred forty-seven patients were scanned (71 with juvenile myoclonic epilepsy, 49 with generalized tonic-clonic seizures only, and 27 with absence epilepsy). Subgroup analyses with corrections for multiple comparisons showed that, when compared with those of controls, anterior thalamic volumes were increased in patients with absence epilepsy and juvenile myoclonic epilepsy with absence seizures, but not in patients with generalized tonic-clonic seizures only and juvenile myoclonic epilepsy without absence seizures. Our results demonstrated that the anterior thalamus is structurally different in patients with IGEs and absence seizures as compared with patients with IGEs without absence seizures.

References

Jan 1, 1991·Neuroscience·G Buzsáki
Mar 1, 1994·Journal of Computer Assisted Tomography·D L CollinsA C Evans
Jun 9, 1998·IEEE Transactions on Medical Imaging·J G SledA C Evans
Jul 7, 2001·Epilepsia·M AvoliG Avanzini
Aug 7, 2003·Brain : a Journal of Neurology·A BernasconiD L Arnold
Nov 26, 2003·Epilepsia·Susana B MoryFernando Cendes
Mar 23, 2004·Brain : a Journal of Neurology·Y AghakhaniJ Gotman
Mar 26, 2005·Current Opinion in Neurology·Benjamin ZifkinFrederick Andermann
Aug 17, 2005·Epilepsy & Behavior : E&B·Steven KarceskiDaniel Carpenter
Sep 9, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Andrea MechelliCathy J Price
Sep 30, 2005·Epilepsia·Margitta SeeckFrancois Lazeyras

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Citations

Jan 28, 2012·AJNR. American Journal of Neuroradiology·E WidjajaM L Smith
Mar 21, 2013·Journal of Neurology·Ji Hyun KimSeong-Beom Koh
Mar 15, 2011·Brain : a Journal of Neurology·Duygu TosunBruce Hermann
Dec 26, 2012·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Tie FangYongjie Li
May 8, 2015·Acta Neurologica Scandinavica·K M ParkS E Kim
Sep 7, 2016·Acta Neurologica Scandinavica·B E SwartzM L Su
Feb 15, 2011·Medical Image Analysis·Bruno AlfanoMarco Salvatore
Feb 27, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Mark Richardson
Jul 28, 2009·Epilepsy & Behavior : E&B·John R Hughes
Jul 25, 2009·Epilepsia·Rochelle CaplanW Donald Shields
Jun 19, 2008·Epilepsia·Rochelle CaplanW Donald Shields
Aug 23, 2008·Epilepsia·Angelos M KatramadosPanayiotis D Mitsias
May 19, 2007·Epilepsia·Fulvio A ScorzaEsper A Cavalheiro
May 17, 2006·NeuroImage·Luiz Eduardo BettingFernando Cendes
Nov 11, 2014·NeuroImage. Clinical·Megan L McGillThomas Thesen
Aug 24, 2010·Seizure : the Journal of the British Epilepsy Association·Nicola SpecchioLucia Fusco
Jan 30, 2013·Epilepsy & Behavior : E&B·Márcia Silva de OliveiraGabriela Castellano
Jun 28, 2011·Epilepsy & Behavior : E&B·Susana Barreto MoryLi M Li
Oct 22, 2016·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kang Min ParkSung Eun Kim
Apr 3, 2008·Neurosurgery·Julie G PilitsisRoy A E Bakay
Mar 31, 2009·Arquivos de neuro-psiquiatria·Fulvio A ScorzaEsper A Cavalheiro
Apr 11, 2018·Epilepsia·Jeffrey R TenneyTracy A Glauser
Jun 4, 2010·Expert Review of Neurotherapeutics·Mark Richardson
Oct 9, 2020·Journal of Clinical Neurology·Eun Hee KimMi Sun Yum
May 16, 2020·Neurotoxicology·Reham Mohammed ShamloulMohammad A Farrag
Aug 19, 2021·Brain Connectivity·Jeffrey R TenneyDarren S Kadis

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