MRI/US fusion-guided prostate biopsy allows for equivalent cancer detection with significantly fewer needle cores in biopsy-naive men

Diagnostic and Interventional Radiology : Official Journal of the Turkish Society of Radiology
Vidhush K YarlagaddaSoroush Rais-Bahrami

Abstract

We aimed to investigate the efficiency and cancer detection of magnetic resonance imaging (MRI) / ultrasonography (US) fusion-guided prostate biopsy in a cohort of biopsy-naive men compared with standard-of-care systematic extended sextant transrectal ultrasonography (TRUS)-guided biopsy. From 2014 to 2016, 72 biopsy-naive men referred for initial prostate cancer evaluation who underwent MRI of the prostate were prospectively evaluated. Retrospective review was performed on 69 patients with lesions suspicious for malignancy who underwent MRI/US fusion-guided biopsy in addition to systematic extended sextant biopsy. Biometric, imaging, and pathology data from both the MRI-targeted biopsies and systematic biopsies were analyzed and compared. There were no significant differences in overall prostate cancer detection when comparing MRI-targeted biopsies to standard systematic biopsies (P = 0.39). Furthermore, there were no significant differences in the distribution of severity of cancers based on grade groups in cases with cancer detection (P = 0.68). However, significantly fewer needle cores were taken during the MRI/US fusion-guided biopsy compared with systematic biopsy (63% less cores sampled, P < 0.001) CONCLUSION: In biopsy-...Continue Reading

Citations

Jul 4, 2019·AJR. American Journal of Roentgenology·Matthias BarralFrançois Cornud
Sep 4, 2019·Current Urology Reports·Annerleim Walton-DiazMauricio Burotto
Nov 11, 2018·Prostate Cancer and Prostatic Diseases·Rachael L SherrerSoroush Rais-Bahrami
Dec 6, 2018·Diagnostics·Kyle H GennaroSoroush Rais-Bahrami
Jun 27, 2019·Prostate Cancer and Prostatic Diseases·Kristin K PorterSoroush Rais-Bahrami

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