PMID: 8592468Jan 1, 1995Paper

MtDNA-encoded histocompatibility antigens

Methods in Enzymology
V M Dabhi, K F Lindahl

Abstract

Mitochondrially encoded H antigens are by-products of a system that has evolved in vertebrates to present peptides from intracellular pathogens on the cell surface for detection by CTLs, which can lyse the infected cell. CTL lines and clones with defined specificity against mitochondrial H antigens, which can be maintained in culture for long periods, offer a unique tool in mitochondrial genetics. Expression of polymorphic mitochondrial H antigens depends on both the presence and the activity of the corresponding mitochondrial genome, and CTLs can provide strong selection against cells displaying their cognate antigen.

Citations

Jan 1, 1997·Annual Review of Immunology·K F LindahlM Yoshino
Dec 8, 1998·European Journal of Immunology·V M Dabhi, K F Lindahl
Mar 25, 2006·Stem Cells·Vanessa J HallMiodrag Stojkovic
Jan 31, 2008·Journal of Translational Medicine·Kaushik Dilip Deb, Kanchan Sarda
Jun 29, 2021·Journal of Biomolecular Structure & Dynamics·Arne StrandJohann Deisenhofer

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