PMID: 11343742May 10, 2001Paper

MUC 1: a genetic susceptibility to infertility?

Lancet
A W HorneE Lalani

Abstract

In man and some animals regulation of embryo implantation by endometrial expression of the highly polymorphic MUC 1 mucin has been suggested. We assessed the polymorphism of MUC 1 in women known to be fertile and those with infertility due to suspected failure of embryo implantation. The median of the lower allele size in the infertile group was only 2.5 kb compared with 3.4 kb in the fertile group (p=0.0029, difference 0.9, [95% CI 0.1-1.3]). Women with unexplained infertility might have a genetic susceptibility to failure of embryo implantation due to small MUC 1 allele size.

References

Dec 14, 1985·British Medical Journal·M G HullK M Desai
Sep 2, 1998·BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology·D D CarsonE G Regisford

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Citations

Jul 26, 2002·Fertility and Sterility·Anette LindhardSteen Sørensen
Jul 18, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·Andrew W HorneEl-Nasir Lalani
May 25, 2002·Acta Obstetricia Et Gynecologica Scandinavica·Kåre Rygaard, Svend Lindenberg
Jun 10, 2009·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Udo JeschkeMarkus S Kupka
Jan 1, 2010·Genetics and Molecular Biology·Fabio Ricardo Pablos de SouzaLucia Regina Martelli
Dec 8, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·Kevin Y Lee, Francesco J DeMayo
Jan 23, 2003·Reproductive Biomedicine Online·A PellicerC Simón
Apr 2, 2002·Neoplasia : an International Journal for Oncology Research·Stephen MitchellEl-Nasir Lalani
May 20, 2004·Reproductive Biomedicine Online·L R GoulartJ G Franco
Jan 27, 2005·Reproductive Biomedicine Online·Diederik A HoozemansPeter G A Hompes
Feb 17, 2007·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·F R P de SouzaL R Martelli
Jun 15, 2011·Reproductive Biomedicine Online·Sarah NordqvistHelena Akerud
Jun 12, 2012·Biochimica Et Biophysica Acta·Y E M KootN S Macklon
Jun 22, 2007·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·D B DentilloL Martelli
Sep 20, 2006·Human Reproduction Update·Hanna Achache, Ariel Revel
Nov 28, 2001·Current Opinion in Neurology·J Jaeken, H Carchon
Feb 14, 2012·Molecular Biology Reports·Chen XiaoWang Aiguo
Jun 3, 2011·Molecular Biology Reports·Fabio Ricardo Pablos de SouzaRoberto Rasero
Feb 19, 2021·Journal of Nanobiotechnology·Lewis W FrancisR Steven Conlan
Oct 7, 2021·Annual Review of Cell and Developmental Biology·Joe Chin-Hun Kuo, Matthew J Paszek

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