PMID: 20635898DOI: 10.2217/imt.10.17Jul 20, 2010Paper
MUC1 immunotherapy
Immunotherapy
Richard E BeatsonJoy M Burchell
Abstract
The overexpression and aberrant glycosylation of MUC1 is associated with a wide variety of cancers, making it an ideal target for immunotherapeutic strategies. This review highlights the main avenues of research in this field, focusing on adenocarcinomas, from the preclinical to clinical; the problems and possible solutions associated with each approach; and speculates on the direction of MUC1 immunotherapeutic research over the next 5-10 years.
References
Apr 1, 1992·Cancer·M R Oakar
May 29, 1992·Biochemical and Biophysical Research Communications·L PembertonS J Gendler
Jan 1, 1992·Cancer·N I WalkerO D Harris
Jan 1, 1988·International Journal of Cancer. Supplement = Journal International Du Cancer. Supplement·S ZotterJ Hilgers
Jun 15, 1989·International Journal of Cancer. Journal International Du Cancer·A GirlingJ Taylor-Papadimitriou
Sep 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·S J GendlerJ Taylor-Papadimitriou
Oct 1, 1987·Annals of Human Genetics·D M SwallowJ Taylor-Papadimitriou
Jul 15, 1981·International Journal of Cancer. Journal International Du Cancer·J ArklieR Millis
May 1, 1995·Cancer·L M MinasianP B Chapman
Oct 1, 1995·British Journal of Cancer·M M GourevitchJ Hilgers
Oct 15, 1995·European Journal of Biochemistry·I BrockhausenJ Taylor-Papadimitriou
Nov 3, 1995·International Journal of Cancer. Journal International Du Cancer·M A McGuckinB G Ward
Apr 1, 1995·The Journal of Cell Biology·J WesselingJ Hilkens
Nov 15, 1994·Cancer·W H KruitG Stoter
Dec 1, 1994·British Journal of Cancer·D W MilesR D Rubens
Aug 1, 1994·The Journal of Experimental Medicine·J S HaurumT Elliott
Dec 20, 1995·Biochimica Et Biophysica Acta·S PattonA P Spicer
Feb 1, 1996·Cancer Immunology, Immunotherapy : CII·R A GrahamJ Taylor-Papadimitriou
Jun 1, 1996·The Journal of Surgical Research·J S GoydosM T Lotze
Jul 1, 1996·Cancer Immunology, Immunotherapy : CII·W M MulderE Bloemena
Jul 1, 1996·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·S von Mensdorff-PouillyJ Hilgers
Oct 1, 1996·British Journal of Cancer·D W MilesR D Rubens
Dec 27, 1996·The Journal of Biological Chemistry·T L GoetzM D Griswold
Dec 27, 1996·The Journal of Biological Chemistry·K O LloydJ Taylor-Papadimitriou
Jan 1, 1997·Cancer Immunology, Immunotherapy : CII·K R JeromeO J Finn
Mar 15, 1997·Cellular Immunology·K ZhangG C Hansson
Apr 1, 1997·European Journal of Nuclear Medicine·O D HughesP A Schubiger
May 1, 1997·Cellular Immunology·M NakaoK Itoh
Jun 16, 1997·The Journal of Cell Biology·C WhitehouseJ Taylor-Papadimitriou
Jul 1, 1997·Scandinavian Journal of Immunology·C M BöhmC Hanski
Jan 14, 1998·Nature Medicine·B AgrawalB M Longenecker
Jun 17, 1998·International Journal of Cancer. Journal International Du Cancer·M ReddishB M Longenecker
Feb 19, 1999·Immunity·A GlitheroT Elliott
May 20, 1999·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·W BruggerL Kanz
Jun 11, 1999·American Journal of Clinical Pathology·G A DentS A Bentley
Aug 3, 1999·The Journal of Experimental Medicine·J S HaurumT Elliott
Nov 24, 1999·Glycobiology·J BurchellJ Taylor-Papadimitriou
Dec 28, 1999·Immunology·D NathP R Crocker
Jan 21, 2000·Cancer·T NittaF Murata
Feb 2, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S von Mensdorff-PouillyJ Hilgers
Jun 9, 2000·Breast Cancer Research and Treatment·D ChenJ Gong
Jun 17, 2000·Vaccine·V ApostolopoulosI F McKenzie
Jul 18, 2000·European Journal of Immunology·V ApostolopoulosI F McKenzie
Aug 10, 2000·Vaccine·C J LeesI F McKenzie
Sep 7, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·P MukherjeeS J Gendler
Nov 9, 2000·The Journal of Immunology : Official Journal of the American Association of Immunologists·S KoidoJ Gong
Dec 7, 2000·Immunology·J GongD Kufe
Dec 29, 2000·The Journal of Biological Chemistry·M DalzielJ Taylor-Papadimitriou
Mar 28, 2001·Science·P M RuddR A Dwek
Mar 30, 2001·The Journal of Biological Chemistry·J A SchroederS J Gendler
❮ Previous
Next ❯
Citations
Aug 11, 2012·Glycoconjugate Journal·Kirstine LavrsenHans H Wandall
Jul 27, 2011·Journal of Mammary Gland Biology and Neoplasia·Tim Kees, Mikala Egeblad
Aug 22, 2013·Biochemical Pharmacology·Yang-Yang HanYu-Qing Chen
Aug 13, 2013·Trends in Molecular Medicine·Salomé S PinhoCelso A Reis
Dec 16, 2011·Proceedings of the National Academy of Sciences of the United States of America·Vani LakshminarayananGeert-Jan Boons
Jul 7, 2011·Cancer Biotherapy & Radiopharmaceuticals·Huguette Albrecht, Kermit L Carraway
Sep 7, 2011·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Margaret A Liu
Nov 27, 2010·American Journal of Physiology. Gastrointestinal and Liver Physiology·J PeterssonM Phillipson
May 23, 2012·Clinical & Developmental Immunology·Lu ZhangJochen Greiner
Jan 4, 2013·PloS One·Brian J MorrisonJ Alejandro Lopez
Sep 28, 2012·Beilstein Journal of Organic Chemistry·Ulrika Westerlind
Oct 2, 2012·International Journal of Oncology·Wei SongDapeng Zhou
Sep 4, 2013·Immunotherapy·Frederick L LockeMohamed A Kharfan-Dabaja
Mar 2, 2011·Therapy·Gregory E HoltLuis E Raez
Nov 6, 2013·Immunotherapy·Stamatis VassilarosVasso Apostolopoulos
Apr 6, 2011·Immunotherapy·Lindzy F DodsonPeter Goedegebuure
Mar 29, 2014·Trends in Molecular Medicine·Sritama Nath, Pinku Mukherjee
Jan 12, 2012·Clinical & Developmental Immunology·Filippo BellatiMarianna Nuti
Nov 12, 2010·Cancer Immunology, Immunotherapy : CII·R Curtis BirdBruce F Smith
Jan 9, 2013·Prostate Cancer and Prostatic Diseases·C SanchezJ F Vera
Oct 3, 2014·Cell Death & Disease·Q ZhaoL-G Yu
Nov 16, 2013·Nature Chemical Biology·Margreet A Wolfert, Geert-Jan Boons
Dec 28, 2011·Expert Review of Endocrinology & Metabolism·Pamela E ConstantinouDaniel D Carson
Jan 6, 2016·International Journal of Molecular Sciences·Sergey V GudkovAndrei V Zvyagin
Jun 23, 2011·Expert Review of Vaccines·Janet Plate
Jun 23, 2011·Expert Review of Vaccines·Frank M SpeetjensSjoerd H van der Burg
Jan 1, 2014·Vaccines·Zhi-Hua HuangYan-Mei Li
Mar 29, 2014·Expert Opinion on Drug Delivery·Rajesh SunaseeRavin Narain
Mar 15, 2012·Expert Opinion on Biological Therapy·Stephen E Wright
Apr 18, 2012·Expert Opinion on Biological Therapy·Carlo GenovaFrancesco Grossi
Dec 3, 2014·ACS Chemical Biology·David MadariagaJesús M Peregrina
Apr 9, 2011·New Biotechnology·Vinochani PillayAndrew M Scott
Jun 15, 2013·Journal of the American Chemical Society·Alison L ParryNeil R Cameron
Oct 6, 2015·Cellular Immunology·Rana FalahatNorma Alcantar
Oct 24, 2012·Chemistry : a European Journal·Brendan L WilkinsonRichard J Payne
Sep 17, 2013·Angewandte Chemie·Lutz NuhnHorst Kunz
Sep 13, 2011·Angewandte Chemie·Nikola GaidzikHorst Kunz
Dec 7, 2011·European Journal of Immunology·David RouloisJean-François Fonteneau
Aug 12, 2014·Chemistry : a European Journal·David MadariagaJesús M Peregrina
Jun 4, 2014·Chembiochem : a European Journal of Chemical Biology·Abu-Baker M Abdel-AalGeert-Jan Boons
Oct 21, 2014·Advanced Healthcare Materials·Sebastian HartmannRudolf Zentel
Nov 21, 2013·Histopathology·Mindaugas AndrulisReinhard Schwartz-Albiez
Mar 20, 2014·Macromolecular Bioscience·Lutz NuhnRudolf Zentel
Jul 1, 2015·Critical Reviews in Oncology/hematology·Alessandro AllegraCaterina Musolino
Aug 21, 2015·Nature Reviews. Cancer·Salomé S Pinho, Celso A Reis
May 3, 2014·Biochimica Et Biophysica Acta·Nicolas JonckheereIsabelle Van Seuningen
May 30, 2015·Chemical Communications : Chem Comm·Pamela ThompsonGeert-Jan Boons
Nov 20, 2013·Biochimica Et Biophysica Acta·Takahiko MatsushitaShin-Ichiro Nishimura
Dec 21, 2014·Glycobiology·Kristin E HaugstadMarit Sletmoen
Dec 17, 2014·Biochemical and Biophysical Research Communications·Solange TréhouxIsabelle Van Seuningen
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Methods Mentioned
BETA
glycosylation
transgenic
ubiquitination
xenograft
transfection
Software Mentioned
Theratope
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