Mucin-hypersecreting tumors of the pancreas: assessing the grade of malignancy preoperatively

American Journal of Surgery
K YamaguchiM Tanaka

Abstract

Mucin-hypersecreting tumor of the pancreas (MHST) is a unique variant of pancreatic tumor, where mucin was excreted from the patulous orifice of the enlarged ampulla of Vater and the main pancreatic duct was dilated with excessive mucin. It is difficult to differentiate preoperatively between benign and malignant variants. A total of 18 patients with an MHST were retrospectively reviewed to identify possible indicators of malignancy. The 18 tumors consisted of 9 benign lesions (hyperplasia or adenoma with mild to moderate atypia), 2 borderline disorders (adenoma with severe atypia), and 7 malignant diseases (unequivocal adenocarcinoma). The age, sex, and site of origin demonstrated no significant difference among the three groups. One of the 9 patients with the benign lesion was diabetic, while 4 of the 7 patients with the malignant variant were diabetic (P<0.05). All 9 benign lesions were confined to the side branch, while 4 of the 7 malignant diseases were located in the main pancreatic duct (P<0.05). The mean greatest diameters of these three variants were 3.2 cm, 3.3 cm, and 6.6 cm, respectively. The mean greatest diameter of the main pancreatic duct in the 7 malignant disorders were larger than in the 9 benign conditions (...Continue Reading

References

Mar 1, 1991·Gastrointestinal Endoscopy·N J NicklP B Cotton
Mar 1, 1991·Gastrointestinal Endoscopy·A L Warshaw
Jul 1, 1990·Gastrointestinal Endoscopy·M A DabeziesA C Friedman
Aug 1, 1989·Human Pathology·M ShimizuY Saitoh
Oct 1, 1987·Radiology·Y ItaiA Terano
Jan 1, 1987·Pancreas·P N RogersW R Murray
Nov 1, 1987·Digestive Diseases and Sciences·A L WarshawD L Gang
Mar 1, 1987·Annals of Surgery·C R ConleyL H Weiland

❮ Previous
Next ❯

Citations

Sep 13, 2006·Abdominal Imaging·Giovanni CarbogninRoberto Pozzi Mucelli
Jul 22, 2006·Journal of Hepato-biliary-pancreatic Surgery·Norihiro Sato, Michael Goggins
Aug 6, 2005·Journal of Gastroenterology·Masao TanakaKoji Yamaguchi
Oct 12, 2007·International Journal of Clinical Oncology·Koki NagaikeHiroaki Kataoka
Jan 20, 2012·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Laura H RosenbergerCharles J Yeo
Nov 8, 2005·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Taketo YamaguchiHiromitsu Saisho
Aug 10, 2000·The British Journal of Surgery·Y ShimaN Tanaka
Mar 22, 2001·The British Journal of Surgery·M FalconiP Pederzoli
Feb 19, 2003·Journal of Clinical Gastroenterology·Toshifumi MatsumotoSeigo Kitano
Jun 20, 2007·Journal of Clinical Gastroenterology·Stavros GourgiotisMarco Pericoli Ridolfini
Aug 19, 2009·Topics in Magnetic Resonance Imaging : TMRI·Young Mi KuRichard C Semelka
Aug 18, 2005·Journal of Gastroenterology and Hepatology·Sun-Young LeeJong Chul Rhee
May 27, 2009·Journal of Gastroenterology and Hepatology·Michael StamatakosMichael Safioleas
Jul 18, 2002·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·K Yamaguchi, M Tanaka
Feb 25, 2006·AJR. American Journal of Roentgenology·Satomi KawamotoElliot K Fishman
Feb 6, 2009·World Journal of Gastroenterology : WJG·Kun-Chun ChiangChun-Nan Yeh
Nov 11, 1999·Radiographics : a Review Publication of the Radiological Society of North America, Inc·C ProcacciG F Pistolesi
Mar 4, 2003·Gastrointestinal Endoscopy·Kelly A ClayMark H Delegge
Nov 15, 2005·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Satomi KawamotoElliot K Fishman
Apr 1, 2008·Journal of Gastroenterology·Masanori SugiyamaYutaka Atomi
Apr 13, 2010·Journal of Gastroenterology·Atsushi KannoTooru Shimosegawa
Sep 1, 2008·Journal of Medical Ultrasonics·Go KobayashiOsamu Takasawa
Apr 11, 2012·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Noritoshi KobayashiKensuke Kubota

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Ductal

Ductal carcinoma is a malignant neoplasm involving the ductal systems of any of a number of organs, such as the mammary glands, pancreas, prostate or lacrimal gland. Discover the latest research on ductal carcinoma here.