Mucormycosis caused by Rhizopus microsporus var. microsporus: cellulitis in the leg of a diabetic patient cured by amputation.

Journal of Clinical Microbiology
B C WestK J Kwon-Chung

Abstract

Mucormycosis accompanied the development of bacterial infection in the leg of a diabetic African-American man. Local injury, diabetic ketoacidosis, renal insufficiency, and antimicrobial therapy were factors that contributed to the pathogenesis of the mucormycosis. The cellulitis was caused in part by Rhizopus microsporus var. microsporus and was cured by amputation. We report this unusual case of mucormycosis to emphasize the value of fungal identification, to illustrate a dramatic and successful clinical result, and to draw attention to an apparent role for bacterial infection and its treatment in the pathogenesis of mucormycosis. It is the third case report of mucormycosis in a human in which R. microsporus var. microsporus was definitively identified as the etiologic agent.

References

Jul 1, 1979·Archives of Surgery·S D CodishA P Monaco
May 1, 1990·Journal of the American Academy of Dermatology·R ClarkB Carroll
Jan 1, 1989·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·M NakamuraD B Kaufman
Jul 1, 1983·Journal of the American Academy of Dermatology·P L MyskowskiD Armstrong
Nov 1, 1983·The American Journal of the Medical Sciences·R S RosenbergerJ W King
Apr 1, 1984·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·T WilsonM A Schipper
Jul 1, 1980·Annals of Internal Medicine
Jul 1, 1983·American Journal of Clinical Pathology·R O BrennanD T Durack
May 1, 1981·The Journal of Hand Surgery·M J Hennessy, T F Mosher

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Citations

Sep 1, 2005·Indian Journal of Pediatrics·S BhadadaA K Gupta
Jan 16, 2014·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Kavita Sachdeva
Aug 5, 2005·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Maureen M RodenThomas J Walsh
Mar 24, 2018·The Pediatric Infectious Disease Journal·Shalu GuptaSuvradeep Mitra
Feb 7, 2001·Clinical Microbiology Reviews·J A RibesD J Baker

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