Mucormycosis experience through the eyes of the laboratory

Infectious Diseases
Pınar SağıroğluFatma Mutlu Sarıgüzel

Abstract

Background: Mucormycosis is a rare, worldwide fungal infection with high mortality, which mostly affects immunocompromised patients. Compared to large parts of Asia, Europe, and the USA, information on clinical expression and fungal species distribution in mucormycosis in Turkey is limited. Objectives and methods: The main aim of this study was to evaluate the demographic features of mucormycosis cases, identify the isolates at the species level by using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF), compare culture results with histopathological examination and determine the antifungal susceptibility patterns of the pathogens. Results: Between 2016 and 2018, 10 mucormycosis cases (six female, four male; age range: 35-74 years) were evaluated retrospectively. The predominance of the cases were in late autumn and winter. Diabetes mellitus was the most common underlying condition. Seven patients had rhinoorbitocerebral, two had pulmonary and one had cutaneous mucormycosis. By mycological culture and direct microscopic examination nine strains were identified as Rhizopus spp. and one as Mucor spp. Seven of these strains were identified at the species level by MALDI-TOF. Histopathological ...Continue Reading

References

Jul 10, 2008·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Georgios ChamilosDimitrios P Kontoyiannis
Sep 17, 2009·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C Lass-Flörl
Jan 25, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·George PetrikkosDimitrios P Kontoyiannis
Sep 12, 2013·Future Microbiology·Russell E Lewis, Dimitrios P Kontoyiannis
Jan 31, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·G PetrikkosM Drogari-Apiranthitou
Jan 31, 2014·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·U BinderC Lass-Flörl
Feb 22, 2016·Infectious Disease Clinics of North America·Dimitrios Farmakiotis, Dimitrios P Kontoyiannis
Nov 4, 2016·Journal of Clinical Microbiology·Maurizio Sanguinetti, Brunella Posteraro
Aug 15, 2017·International Journal of Antimicrobial Agents·E Dannaoui
Oct 14, 2017·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·V L KungC-A D Burnham
Dec 12, 2017·Antimicrobial Resistance and Infection Control·Shobini SivagnanamSteven A Pergam
Mar 15, 2018·Medical Mycology·A SkiadaG Petrikkos
Jul 24, 2018·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·W JeongS C-A Chen
Aug 2, 2018·Journal of Fungi·Nikolaos V SipsasDimitrios P Kontoyiannis
Mar 17, 2019·Journal of Fungi·Alexandra SerrisFanny Lanternier
Mar 23, 2019·Journal of Fungi·Laurence MillonAnne-Pauline Bellanger
Mar 25, 2019·Journal of Fungi·Hariprasath Prakash, Arunaloke Chakrabarti
Apr 17, 2019·Journal of Food and Drug Analysis·Tsung-Yun HouShih-Hua Teng

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Citations

Nov 23, 2020·The Australasian Journal of Dermatology·Alexandro BonifazGloria M González
Nov 8, 2020·Enfermedades infecciosas y microbiología clínica·Alexandro BonifazGloria M González

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