PMID: 46141Jan 1, 1975

Mucosal histochemistry in secretory otitis

The Annals of Otology, Rhinology, and Laryngology
T Palva, A Palva


Mucosal biopsies were taken from 20 ears with secretory otitis media (glue ear) and histochemical stainings were made for comparison with data obtained from biochemical analysis of the fluids. Acid phosphatase, lactate dehydrogenase (LD), and malate dehydrogenase (MD), the activity of which in the ear fluids was 20 to 30 times higher than in serum, were found to appear as strong precipitates in the middle ear epithelium, particularly in the top layer. Alkaline phosphatase activity was only exceptionally seen in the epithelium but appeared in the capillaries and histiocytes. Nonspecific esterase appeared irregularly in the epithelium and regularly in histiocytes. The latter two had lower activities in ear fluids than in serum. Epithelial secretory cells and subepithelial glands and cysts showed strong alcian blue (AB)-positive staining. Positive material appeared also in the cytoplasm of the epithelial cells and in the intercellular substance. Distinct PAS-positive staining appeared in the columnar epithelium and particularly in the free mucus on top of the epithelium but was less promounced in the glandular structures and absent from the cysts.


Jan 1, 1984·Acta Oto-laryngologica. Supplementum·J M van der Beek, W Kuijpers
Jan 1, 1984·Acta Oto-laryngologica. Supplementum·W Kuijpers, J M van der Beek
Jan 1, 1981·International Journal of Pediatric Otorhinolaryngology·T PalvaJ Rinne
May 1, 1979·The Annals of Otology, Rhinology, and Laryngology·J M BernsteinE R Hayes
Jul 1, 1977·The Annals of Otology, Rhinology, and Laryngology·M M PaparellaS Giebink
Jan 15, 2016·Veterinary Clinical Pathology·Nicole M WeinsteinJohn Rossmeisl


May 1, 1971·Archives of Otolaryngology·O Tönder, T Gundersen
Jun 1, 1971·The Annals of Otology, Rhinology, and Laryngology·S K JuhnM M Paparella
Jul 1, 1972·Archives of Otolaryngology·T Gundersen, E Glück
Jan 1, 1973·Acta Oto-laryngologica·M Tos, K Bak-Pedersen
May 1, 1973·The Annals of Otology, Rhinology, and Laryngology·G MogiT Yoshida
Jan 1, 1970·Archives of Otolaryngology·T PalvaK Dammert
Mar 1, 1974·The Annals of Otology, Rhinology, and Laryngology·T PalvaR Nousianen
Apr 1, 1973·Acta Oto-laryngologica·M Tos, K Bak-Pedersen
Sep 1, 1966·Archives of Otolaryngology·J Sade
Jan 1, 1955·Scandinavian Journal of Clinical and Laboratory Investigation·L A CARLSON, T LOKK

Related Concepts

Acid Phosphatase
Disorder of Middle Ear
Malignant Neoplasm of Middle Ear
Entire Middle Ear
Columnar Epithelium
Ear Inflammation
Malate Dehydrogenase
Squamous Transitional Epithelial Cell Count

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