PMID: 1202919Nov 1, 1975Paper

Mucosal malignant melanomas of the head and neck with special reference to cases having a prolonged clinical course

Acta Oto-laryngologica
C M Eneroth, C Lundberg

Abstract

A histological re-examination and re-classification of primary mucosal tumours of the head and neck region, treated at Radiumhemmet and Karolinska Sjukhuset during the period 1927-1970, revealed that 41 tumours were malignant melanomas. All these 41 tumours were located in the nasal cavity, paranasal sinuses and oral cavity and not a single case of primary mucosal malignant melanoma was found in other locations of the head and neck region. In the present study, the long-term prognosis has been analysed. The follow-up period was at least 5 years and ranged up to 48 years. It was found that mucosal malignant melanomas had a very poor prognosis with a five year survival rate of 17% (7 of the total 41 cases) and a ten year survival rate of 7% (3 of the total of 41 cases). The unpredictability of the clinical behaviour of this tumour type is elucidated by cases with a prolonged clinical course despite a primary relatively limited surgery, repeated local recurrences and regional lymph node metastases in an early stage of the disease. Thus, there is always a never-ceasing risk of death in the tumour disease when once a malignant melanoma has occurred. For this reason a meticulous and lifelong follow-up of tumour patients is stressed, ...Continue Reading

References

Apr 1, 1973·Archives of Otolaryngology·H M FreedmanL H Weiland
Feb 1, 1969·The Annals of Otology, Rhinology, and Laryngology·J Holdcraft, J C Gallagher
Apr 1, 1967·The American Journal of Roentgenology, Radium Therapy, and Nuclear Medicine·D Catlin
Nov 1, 1955·Cancer·E S MOORE, H MARTIN
Feb 1, 1955·The Journal of Laryngology and Otology·M MASON, I FRIEDMANN

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Citations

Apr 22, 2003·Pathology Oncology Research : POR·Erzsébet LengyelOlga Esik
Oct 31, 2003·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Alexander D RapidisSpyros Valsamis
Jul 9, 2003·Clinical Oncology : a Journal of the Royal College of Radiologists·N W YiiM E Gore
Nov 1, 1976·The Journal of Laryngology and Otology·D F Harrison
Apr 21, 1998·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·S RegauerA Beham
Sep 9, 2008·The Bulletin of Tokyo Dental College·Daisuke NakamotoTakahiko Shibahara
Jul 1, 1994·Journal of Veterinary Internal Medicine·K E BatemanS A Kruth
Jul 1, 1985·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·M W DewhirstE Bicknell
Mar 28, 2002·European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP)·M PandeyK M Nair
Apr 1, 1991·Journal of the American Academy of Dermatology·D Eisen, J J Voorhees
Jul 21, 2004·Journal of Cranio-maxillo-facial Surgery : Official Publication of the European Association for Cranio-Maxillo-Facial Surgery·Paolo Garzino-DemoSid Berrone
May 1, 1980·American Journal of Surgery·K Iversen, R E Robins
Mar 1, 1986·Head & Neck Surgery·W R Panje, W J Moran
Jul 1, 1994·Oral Surgery, Oral Medicine, and Oral Pathology·N TanakaS F Reck
Sep 1, 1990·Clinical Oncology : a Journal of the Royal College of Radiologists·M N GazeJ F Smyth
Feb 6, 2007·Journal of the Chinese Medical Association : JCMA·Yen-Fu ChengChing-Zong Lin
Feb 1, 1996·The Journal of Laryngology and Otology·R XavierA Gameiro dos Santos
Jul 20, 2002·The American Journal of Surgical Pathology·Manju L PrasadKlaus J Busam
Dec 4, 2004·Cancer·Stephane TemamBernard Luboinski
Dec 15, 2015·Journal of Surgical Oncology·Cecilia G Ethun, Keith A Delman
Sep 29, 1984·British Medical Journal·J S Scott
Sep 29, 1984·British Medical Journal·F H Rampen
Mar 1, 1994·The Journal of Laryngology and Otology·I J JohnsonJ C Watkinson
Sep 1, 1978·Head & Neck Surgery·G B SnowE A van Slooten
May 1, 1982·Head & Neck Surgery·J G BatsakisD H Rice
Nov 1, 1983·Journal of Surgical Oncology·H J ZirkinM Puterman
Apr 1, 1986·Histopathology·I J JeffreyW R Lee
Apr 1, 1982·The Journal of Laryngology and Otology·V Lund
Nov 1, 1979·Head & Neck Surgery·J W Birns, H A Jenkins
Jan 1, 1991·Head & Neck·S J Stern, O M Guillamondegui
Jan 1, 2013·The Journal of Contemporary Dental Practice·Anila KarunakaranM K Shruthi Laxmi
Apr 6, 2004·Surgical Oncology Clinics of North America·Larry L Myers, Lance E Oxford

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