Mullerian adenosarcoma with sarcomatous overgrowth of the cervix presenting as cervical polyp: a case report and review of the literature

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society
H M ParkS C Kim

Abstract

An aggressive variant of adenosarcoma, mullerian adenosarcoma with sarcomatous overgrowth (MASO) in the cervix is extremely rare. This variant contains obvious, high-grade sarcoma in addition to a low-grade form. In this report, we describe a case of MASO of the uterine cervix and review the clinical and pathological features of these tumors. The patient was a 37-year-old woman with a cervical polypoid mass, which was morphologically considered as a benign endocervical polyp. Microscopically, polypoid cervical mass showed diffuse and dense malignant spindle cell proliferation around the benign endocervical glands and also an area of markedly anaplastic and pleomorphic spindle cell proliferation, so called, sarcomatous overgrowth. Total abdominal hysterectomy and bilateral salpingo-oophorectomy with pelvic lymph node dissection were performed. The patient has been followed-up and neither chemotherapy nor other adjuvant therapies have been administered. At present, she has been clinically free of disease for 9 months since she received surgery. It is extremely rare that MASO of the uterine cervix is presented in premenopausal woman. Gynecologists and pathologists should be aware of the difficulties associated with a delay in the ...Continue Reading

References

Mar 1, 1978·American Journal of Clinical Pathology·P B Clement, R E Scully
Jan 1, 1992·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·T KakuM F Brady
Sep 1, 1992·Journal of Surgical Oncology·M HallakG M Schauer
Nov 1, 1988·Gynecologic Oncology·D GalE Paldi
Jun 1, 1981·Human Pathology·C K TangB Harriman
Jul 1, 1995·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·M W Jones, M Lefkowitz
Apr 16, 1998·Pathology·K A SikarisM D Guerin
Jul 2, 1998·Pathology International·M FukunagaS Ushigome
Mar 10, 2001·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·R. Blom, C. Guerrieri
Jan 10, 2002·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Ayse D DincerRobert A Ambros
Oct 3, 2002·The American Journal of Surgical Pathology·John H EichhornRobert E Scully
Oct 9, 2002·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Y NagaiH Ishikura

❮ Previous
Next ❯

Citations

Aug 18, 2009·Archives of Gynecology and Obstetrics·Rashmi BaggaFiroza Patel
Sep 7, 2012·Case Reports in Obstetrics and Gynecology·Slim CharfiTahya Sellami-Boudawara
Mar 16, 2013·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Pui-See ChinKwai-Lam Yam
Nov 16, 2007·Journal of Women's Health·Catherine E BerzollaJoel I Sorosky
May 18, 2011·BMC Cancer·Tito S PatrelliAlberto Bacchi Modena
Sep 14, 2016·International Journal of Surgery Case Reports·David A Morales FIsabel C Dulcey
Oct 9, 2016·Current Oncology Reports·Michael J NathensonAnthony Conley
Jul 12, 2011·Best Practice & Research. Clinical Obstetrics & Gynaecology·Emanuela D'Angelo, Jaime Prat
Jun 21, 2007·Upsala Journal of Medical Sciences·Nil ComunoğluZerrin Calay
Apr 19, 2011·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Sung Jong LeeSung Eun Namkoong

❮ Previous
Next ❯

Related Concepts

Related Feeds

Adenosarcoma

Adenosarcoma is a rare tumor found in women and is located in the uterus, but can also arise in the cervix and ovaries. Discover the latest research on Adenosarcoma here.