Multi-heme cytochromes provide a pathway for survival in energy-limited environments

Science Advances
Xiao DengAkihiro Okamoto

Abstract

Bacterial reduction of oxidized sulfur species (OSS) is critical for energy production in anaerobic marine subsurfaces. In organic-poor sediments, H2 has been considered as a major energy source for bacterial respiration. We identified outer-membrane cytochromes (OMCs) that are broadly conserved in sediment OSS-respiring bacteria and enable cells to directly use electrons from insoluble minerals via extracellular electron transport. Biochemical, transcriptomic, and microscopic analyses revealed that the identified OMCs were highly expressed on the surface of cells and nanofilaments in response to electron donor limitation. This electron uptake mechanism provides sufficient but minimum energy to drive the reduction of sulfate and other OSS. These results suggest a widespread mechanism for survival of OSS-respiring bacteria via electron uptake from solid minerals in energy-poor marine sediments.

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Citations

Nov 2, 2018·Bioscience, Biotechnology, and Biochemistry·Satoshi Wakai
Jan 14, 2020·Nanotechnology·Mon Oo YeeAmelia-Elena Rotaru
Sep 18, 2020·Microbial Biotechnology·Jaspreet Mand, Dennis Enning
Sep 18, 2020·Environmental Microbiology·Alexandra L McCully, Alfred M Spormann
Jun 9, 2020·Frontiers in Bioengineering and Biotechnology·Valeria AgostinoMiriam A Rosenbaum
May 16, 2019·MBio·Hai-Yan TangDerek R Lovley
Jan 20, 2020·World Journal of Microbiology & Biotechnology·Kartik S Aiyer
Sep 16, 2020·Journal of Industrial Microbiology & Biotechnology·Dinesh GuptaArpita Bose
Jul 3, 2021·Frontiers in Microbiology·Mauro Degli EspostiLars Hederstedt
Sep 21, 2021·Frontiers in Microbiology·Arkadiy I GarberNancy Merino
Aug 12, 2021·Applied and Environmental Microbiology·C P CasarM R Osburn
Nov 9, 2021·Environmental Science & Technology·Dandan LiangDerek R Lovley

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Methods Mentioned

BETA
PCA
electrophoresis
Scanning electron microscopy
Transmission electron microscopy
Fluorescence microscopy

Software Mentioned

TopHat
GUIDANCE
MASCOT
MiGAP
MEGA
Matrix
Psortb
MUSCLE
SMRT

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