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Multi-input RNAi-based logic circuit for identification of specific cancer cells

Science

Sep 2, 2011

Zhen XieYaakov Benenson

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Abstract

Engineered biological systems that integrate multi-input sensing, sophisticated information processing, and precisely regulated actuation in living cells could be useful in a variety of applications. For example, anticancer therapies could be engineered to detect and respond to complex ...read more

Mentioned in this Paper

Transfection
Apoptosis, Intrinsic Pathway
Tumor Cells, Malignant
RNA, Small Temporal
Esthesia
Apoptosis regulator BAX, membrane isoform alpha protein, human
Tumor Markers
Cosuppression
MicroRNAs
Apoptosis
43
6
4
770
1
3
Paper Details
References
  • References34
  • Citations246
12345...

Multi-input RNAi-based logic circuit for identification of specific cancer cells

Science

Sep 2, 2011

Zhen XieYaakov Benenson

PMID: 21885784

DOI: 10.1126/science.1205527

Abstract

Engineered biological systems that integrate multi-input sensing, sophisticated information processing, and precisely regulated actuation in living cells could be useful in a variety of applications. For example, anticancer therapies could be engineered to detect and respond to complex ...read more

Mentioned in this Paper

Transfection
Apoptosis, Intrinsic Pathway
Tumor Cells, Malignant
RNA, Small Temporal
Esthesia
43
6
4
770
1
3
Paper Details
References
  • References34
  • Citations246
12345...

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