Multi-institutional comparison of computer-based independent dose calculation for intensity modulated radiation therapy and volumetric modulated arc therapy

Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)
Tatsuya KamimaHidenobu Tachibana

Abstract

No multi-institutional studies of computer-based independent dose calculation have addressed the discrepancies among radiotherapy treatment planning systems (TPSs) and the verification programs for intensity modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT). We conducted a multi-institutional study to investigate whether ±5% is a reasonable action level for independent dose calculation for IMRT/VMAT. In total, 477 IMRT/VMAT plans for prostate or head and neck (H&N) malignancies were retrospectively analyzed using a modified Clarkson-based commercial verification program. The doses from the TPSs and verification programs were compared using the mean ±1 standard deviation (SD). In the TPS-calculated dose comparisons for prostate and H&N malignancies, the sliding window (SW) technique (-2.5 ± 1.8% and -5.3 ± 2.6%) showed greater negative systematic differences than the step-and-shoot (S&S) technique (-0.3 ± 2.2% and -0.8 ± 2.2%). The VMAT dose differences for prostate and H&N malignancies were 0.9 ± 1.8% and 1.1 ± 3.3%, respectively. The SDs were larger for the H&N plans than for the prostate plans in both IMRT and VMAT. Such plans including more out-of-field control points showed greater systematic di...Continue Reading

Citations

Mar 13, 2020·Practical Radiation Oncology·Pietro MancosuMarta Scorsetti

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