Multi-unit relations among neural, self-report, and behavioral correlates of emotion regulation in comorbid depression and obesity

Scientific Reports
Adam R PinesLeanne M Williams

Abstract

Depression is a leading cause of disability and is commonly comorbid with obesity. Emotion regulation is impaired in both depression and obesity. In this study, we aimed to explicate multi-unit relations among brain connectivity, behavior, and self-reported trait measures related to emotion regulation in a comorbid depressed and obese sample (N = 77). Brain connectivity was quantified as fractional anisotropy (FA) of the uncinate fasciculi, a white matter tract implicated in emotion regulation and in depression. Use of emotion regulation strategies was assessed using the Emotion Regulation Questionnaire (ERQ). We additionally measured reaction times to identifying negative emotions, a behavioral index of depression-related emotion processing biases. We found that greater right uncinate fasciculus FA was related to greater usage of suppression (r = 0.27, p = 0.022), and to faster reaction times to identifying negative emotions, particularly sadness (r = -0.30, p = 0.010) and fear (r = -0.35, p = 0.003). These findings suggest that FA of the right uncinate fasciculus corresponds to maladaptive emotion regulation strategies and emotion processing biases that are relevant to co-occurring depression and obesity. Interventions that c...Continue Reading

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Citations

Nov 5, 2019·The Spanish Journal of Psychology·Pablo Ezequiel Flores-KanterLeonardo Adrián Medrano

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Methods Mentioned

BETA
imaging technique

Software Mentioned

AFQ
ENGAGE
RAINBOW

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