Multicenter Assessment of Grafts in Coronaries: Midterm Evaluation of the C-Port Device (the MAGIC Study)

Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery
Husam H BalkhyMAGIC Study Investigators

Abstract

The commercially available C-Port distal anastomotic device (Food and Drug Administration cleared in 2007) is an automated miniature vascular stapler that performs the coronary anastomosis. This prospective multicenter registry sought to evaluate midterm patency using this device compared with hand-sewn grafts. Patients receiving at least one C-Port anastomosis during coronary artery bypass grafting surgery were enrolled at eight sites. Of the 117 patients enrolled, 78 patients (67%) with 104 C-Port vein grafts completed the study to patency assessment via computed tomography angiography. Clinical follow-up and index graft patency (Gated 64-slice computed tomography scan) were performed at least 12 months postoperatively. The primary efficacy endpoint was patency compared with the peer-reviewed results from the PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) trial. The patient population was consistent with the PREVENT IV placebo cohort. The mortality at 12 months was 0.85% (1/117). The major cardiac morbidity rate was 3.4% (4/117). The C-Port vein graft occlusion rate was 16.3% (17/104) compared with 26.6% (597/2242) in the PREVENT IV trial (P = 0.011). Within this study, C-Port graft occlusion rates...Continue Reading

References

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Citations

Aug 30, 2019·Current Opinion in Cardiology·Etem CaliskanVolkmar Falk
Mar 9, 2021·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·David StecherMarc P Buijsrogge
Jul 24, 2021·Interventional Cardiology·Karel M Van PraetStephan Jacobs
Aug 16, 2021·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Husam H BalkhyCharocka Coleman
Oct 28, 2019·The Journal of Thoracic and Cardiovascular Surgery·Dawn S Hui, Richard Lee
Oct 28, 2019·The Journal of Thoracic and Cardiovascular Surgery·Makoto HashimotoHusam H Balkhy
Dec 11, 2021·The Annals of Thoracic Surgery·Husam H BalkhyKaitlin Grady

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