Multicenter randomized prospective trial comparing a pre-cuffed polytetrafluoroethylene graft to a vein cuffed polytetrafluoroethylene graft for infragenicular arterial bypass

Annals of Vascular Surgery
J M PannetonJan Hofer

Abstract

Poor patency of synthetic grafts for infragenicular revascularization has led to use of distal vein patches or cuffs. The aim of this study was to compare the distally widened Distaflo PTFE graft, which mimics a vein cuff, with a PTFE graft with distal vein modification. In this prospective, randomized, multicenter trial we compared use of a precuffed PTFE graft wit that of PTFE grafts with distal vein modification for infragenicular revascularization in patients with critical limb ischemia without saphenous vein. Study end points were primary and secondary patency and limb salvage rates at 2 years. From January 28,1999 to November 1, 2000, 104 patients were enrolled in 10 North American centers. Thirteen were excluded for protocol violation. Ninety-one bypasses were performed in 89 patients with a mean age of 73 years (range 47-90). By randomization, 47 bypasses were done with the precuffed graft and 44 with PTFE graft with vein cuff. Both groups were comparable for comorbidities and operative variables, except for a higher incidence of acute ischemia in the precuffed group (19% vs. 4.5%, p = 0.03). Bypass was a redo procedure in 53% and was performed at the infrapopliteal vessels in 79%. Operative mortality was 2.2% (2/91). M...Continue Reading

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Citations

Dec 17, 2008·Annals of Biomedical Engineering·F L Xiong, C K Chong
Dec 24, 2013·Annals of Vascular Surgery·Steven J TuijpLyckle van der Laan
Jun 12, 2012·Annals of Vascular Surgery·Peter A StonebridgeGraeme Houston
Mar 15, 2011·Annals of Vascular Surgery·Kenneth R ZieglerAlan Dardik
May 24, 2012·The British Journal of Surgery·C P TwineL J Fligelstone
Oct 9, 2015·Tissue Engineering. Part B, Reviews·Samand Pashneh-TalaFrederik Claeyssens
Oct 18, 2011·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·D M ScharnJ A van der Vliet
Sep 5, 2006·Journal of Vascular Surgery·Peter J FahnerDink A Legemate
Feb 5, 2013·Journal of Vascular Surgery·James T McPheeMatthew T Menard
Jul 7, 2014·Journal of Vascular Surgery·Charles A HartranftThomas Hartranft
Mar 4, 2006·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·S SarkarA M Seifalian
Jul 24, 2012·Seminars in Vascular Surgery·Richard F Neville, Anton N Sidawy
Dec 25, 2007·Journal of Vascular Surgery·Andres SchanzerMichael S Conte
Sep 12, 2008·Vascular and Endovascular Surgery·Iosif GulkarovThomas S Maldonado
Sep 14, 2012·The Cochrane Database of Systematic Reviews·Ahmed A M KhalilGareth Griffiths
Mar 24, 2007·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Taiji WatanabeYasuhide Nakayama
Aug 12, 2005·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Osamu SakaiHitoshi Yaku
Jun 2, 2012·Expert Review of Cardiovascular Therapy·Michael J CollinsAlan Dardik
Apr 4, 2017·The Cochrane Database of Systematic Reviews·George A AntoniouFrancesco Torella
Apr 17, 2012·Diabetes & Vascular Disease Research : Official Journal of the International Society of Diabetes and Vascular Disease·Alexander OberhuberBernd M Muehling
Apr 12, 2017·Interactive Cardiovascular and Thoracic Surgery·Tsukasa OzawaYoshinori Watanabe

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