Multicenter, Randomized Trial of Conventional Balloon Angioplasty versus Paclitaxel-Coated Balloon Angioplasty for the Treatment of Dysfunctioning Autologous Dialysis Fistulae

Journal of Vascular and Interventional Radiology : JVIR
Geert MaleuxNicolas Verbeeck

Abstract

To investigate the potential added value of paclitaxel-coated balloon (PCB) angioplasty to reduce fistula dysfunction related to recurrent stenoses in patients undergoing hemodialysis. A prospective, randomized study was conducted in 3 dialysis referral centers. From January 2013 to October 2015, 64 patients (22 female, 42 male) with dysfunctional autologous dialysis fistulae were randomized to undergo conventional percutaneous balloon angioplasty (n = 31) or PCB angioplasty (n = 33). Procedural and postprocedural data were assessed. Primary patency of the fistula was evaluated at 3, 6, and 12 months following the procedure. Statistical analysis was based on the Fisher exact test and independent t test. There were no procedural or postprocedural complications. After 3, 6, and 12 months of follow-up, primary patency rates after PCB angioplasty and percutaneous transluminal angioplasty (PTA) were 88% and 80% (P = .43), 67% and 65% (P = .76), and 42% and 39% (P = .95), respectively. Although primary patency rates after PCB angioplasty in autologous dialysis fistulae at 3, 6, and 12 months of follow-up are slightly better than those after PTA, the difference is not statistically significant.

Citations

Feb 12, 2020·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Zhanjiang CaoWeiwei Wu
Aug 29, 2019·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Krystal DinhRamon L Varcoe
Jul 31, 2020·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jong Woo KimJi Hoon Shin
Jan 9, 2021·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Yanqi YinQizhuang Jin
Dec 5, 2020·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Scott O TrerotolaTheodore F Saad
Jan 2, 2021·Journal of Vascular Surgery·Gregory TripsianisMiltos K Lazarides
Feb 16, 2021·Progress in Cardiovascular Diseases·John A Bittl
Aug 8, 2021·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Khi Yung FongChow Wei Too
Aug 24, 2021·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·Ahram HanSeung-Kee Min
Jul 8, 2021·Cardiovascular and Interventional Radiology·Ounali JafferJason Wilkins

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