PMID: 369922Jan 1, 1979Paper

Multicentre study of 'Flagyl' in the prevention of post-operative anaerobic infection

The Journal of International Medical Research
J GoultonP G Baker

Abstract

In a study carried out with 565 patients undergoing gynaecological and general surgical procedures, metronidazole ('Flagyl') was used pre- and post-operatively and the incidence of post-operative infection, particularly that due to anaerobic organisms, was recorded. This was not a controlled study but, by comparison with other series, it would appear that the use of oral metronidazole had substantially reduced the likelihood of supervention of anaerobic sepsis. It is probable that the use of intravenous metronidazole therapy would have reduced the incidence of anaerobic sepsis still further had this preparation been available at the time.

References

Jul 10, 1976·Lancet·J E HaleG Smith
May 1, 1975·Antimicrobial Agents and Chemotherapy·F P TallyS M Finegold
Dec 1, 1975·The Journal of Antimicrobial Chemotherapy·A R SalemJ A McFadzean
Oct 4, 1975·British Medical Journal·H R InghamR Weiser

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