Multicompartment pharmacokinetic analysis and simulations using a programmable calculator

International Journal of Bio-medical Computing
S Niazi

Abstract

This paper describes the use of a programmable calculator (HP-97), for fitting plasma concentration profiles to 1 and 2 compartment open models and calculating fitted and derived parameters together with estimates of steady state plasma drug levels following various dosage regimens in clinical settings.

References

Jul 1, 1976·Journal of Pharmaceutical Sciences·A J Sedman, J G Wagner
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