Multidimensional system biology: genetic markers and proteomic biomarkers of adverse pregnancy outcome in preterm birth.

American Journal of Perinatology
Catalin S BuhimschiIrina A Buhimschi

Abstract

Premature birth before 37 weeks of gestation is a significant public health problem. Each year, 4.5 million premature infants are born worldwide. Despite extensive research and a variety of interventions, the rate of preterm birth has steadily increased over the past 20 years and reached a high of 12.8% in 2006. The etiology of most preterm births remains elusive and is likely multifactorial, with many pathophysiological pathways involved, such as excessive stretching, oxidative stress, decidual hemorrhage, and infection. Genomics and proteomics have emerged to provide a better comprehension of the pathophysiological conditions leading to preterm birth, thereby providing a perspective for improving neonatal outcome.

Citations

Apr 28, 2009·Current Opinion in Infectious Diseases·Catalin S BuhimschiIrina A Buhimschi
Oct 31, 2008·Journal of Clinical Microbiology·Yiping W HanCatalin S Buhimschi
Mar 27, 2010·BMC Pregnancy and Childbirth·Michael G GravettUNKNOWN GAPPS Review Group
May 20, 2014·American Journal of Epidemiology·Jie QiuYawei Zhang
Nov 3, 2010·Expert Reviews in Molecular Medicine·Catalin S BuhimschiCharles J Lockwood
Sep 9, 2015·American Journal of Obstetrics and Gynecology·Sherrine A IbrahimDouglas A Kniss
Oct 17, 2013·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Carolyn M Allen, Sandra A Founds
Mar 6, 2012·Placenta·J S HortonG D Bryant-Greenwood
Nov 26, 2010·Seminars in Perinatology·Lavone E SimmonsMichael G Gravett
Sep 4, 2010·Clinics in Perinatology·Tara M Randis
Jun 24, 2010·Clinics in Perinatology·Irina A Buhimschi, Catalin S Buhimschi
Jan 13, 2010·Best Practice & Research. Clinical Obstetrics & Gynaecology·Ruth Landau
Apr 20, 2013·Reproductive Sciences·Beena D Kamath-RayneArdythe L Morrow
Oct 25, 2008·BJOG : an International Journal of Obstetrics and Gynaecology·C S BuhimschiI A Buhimschi
Dec 24, 2008·Obstetrics and Gynecology·Catalin S Buhimschi, Carl P Weiner
May 10, 2016·The Journal of Clinical Endocrinology and Metabolism·John T HardyCatalin S Buhimschi

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