Multidirectional myocardial systolic function in hemodialysis patients with preserved left ventricular ejection fraction and different left ventricular geometry

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
Hong WangBin Yang

Abstract

Multidirectional myocardial strain analysis can provide mechanistic insight into the ventricular systolic function and pathophysiology. The aim of this study was to assess the multidirectional systolic function of the left ventricle (LV) and its relationship to LV geometry in hemodialysis patients with preserved left ventricular ejection fraction (LVEF). A total of 98 end-stage renal disease patients (age 46 ± 10 years, 60% men) with preserved LVEF (≥50%) on a maintenance hemodialysis program and 18 healthy volunteers were enrolled. The patients were divided into non-hypertrophic groups (classified as normal LV geometry and concentric remodeling) and hypertrophy groups (classified as eccentric and concentric hypertrophy) according to their LV geometries assessed from LV mass/height(2.7) and relative wall thickness in combination. Multidirectional strain analysis was performed by two-dimensional speckle tracking echocardiography. Myocardial systolic strain (longitudinal and circumferential) and stress-corrected midwall fraction shorting (sc-MWFS) were lower in the hypertrophy groups compared with non-hypertrophic groups. Longitudinal strain and strain rate were even lower in the concentric hypertrophy group than the eccentric hy...Continue Reading

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Citations

Apr 23, 2014·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Diana Y Y ChiuPhilip A Kalra
Feb 12, 2014·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Rathika KrishnasamyTony Stanton
Oct 13, 2015·Nephrology·Toshihide HayashiHiroki Hase
Dec 19, 2015·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Maren Leifheit-NestlerDieter Haffner
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Jun 4, 2016·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·James RitchiePhilip A Kalra
Dec 29, 2018·The Egyptian Heart Journal : (EHJ) : Official Bulletin of the Egyptian Society of Cardiology·Abeer M ShawkyAsmaa A Elmadbouly
Aug 28, 2021·Journal of Personalized Medicine·Ling LinHildo J Lamb

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