Multidrug resistant Aeromonas spp. isolated from zebrafish (Danio rerio): antibiogram, antimicrobial resistance genes and class 1 integron gene cassettes

Letters in Applied Microbiology
Sabrina HossainGang-Joon Heo

Abstract

Aeromonas spp. are Gram-negative opportunistic bacteria which have been commonly associated with fish diseases. In this study, antibiogram, antimicrobial resistance genes and integrons of 43 zebrafish-borne Aeromonas spp. were studied. The isolates were identified as six Aeromonas species (A. veronii biovar veronii (n = 26), A. veronii biovar sobria (n = 3), A. hydrophila (n = 8), A. caviae (n = 3), A. enteropelogenes (n = 2) and A. dhakensis (n = 1)). Antibiogram of the isolates indicated that most of them were resistant to amoxicillin (100·00%), nalidixic acid (100·00%), oxytetracycline (100·00%), ampicillin (93·02%), tetracycline (74·42%), rifampicin (67·44%) and imipenem (65·15%). Multiple antimicrobial resistance (MAR) index values ranged from 0·19-0·44 to 90·70% isolates showed multidrug resistance. PCR of antimicrobial resistance genes revealed that the tetracycline resistance gene (tetA) was the most predominant (67·44%) among the isolates. The qnrS (53·49%), tetB (30·23%), tetE (30·23%), qnrB (23·26%) and aac(6')-Ib-cr (4·65%) genes were also detected. Class 1 integrase (IntI1) gene was found in 46·51% of the isolates. Two types of class 1 integron gene cassette profiles (qacG-aadA6-qacG and drfA1) were identified. The...Continue Reading

References

Jan 26, 2000·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·M Sunde, H Sørum
Sep 15, 2000·Clinical Chemistry and Laboratory Medicine : CCLM·M C PloyF Denis
Jun 17, 2003·International Journal of Systematic and Evolutionary Microbiology·M A YáñezA J Martínez-Murcia
Feb 26, 2004·Antimicrobial Agents and Chemotherapy·Robert S BarlowKari S Gobius
Jul 18, 2006·Nature Reviews. Microbiology·Didier Mazel
Sep 7, 2006·Antimicrobial Agents and Chemotherapy·Chi Hye ParkDavid C Hooper
Jan 13, 2010·Clinical Microbiology Reviews·J Michael Janda, Sharon L Abbott
Feb 26, 2010·The Journal of Antimicrobial Chemotherapy·Stefan SchwarzWim Gaastra
Jul 19, 2011·Applied and Environmental Microbiology·Kristina KadlecStefan Schwarz
Nov 30, 2011·The Journal of Veterinary Medical Science·Mintra LukkanaRungtip Chuanchuen
Mar 21, 2012·Zebrafish·Leon CantasHenning Sørum
Sep 8, 2012·Annals of the New York Academy of Sciences·Ruth M Hall
Dec 7, 2013·Environmental Toxicology and Chemistry·Yu-Jie DaiDe-Sheng Pei
Oct 22, 2015·Annals of Clinical Microbiology and Antimicrobials·Yang DengGuangchao Yu
Mar 24, 2017·The Journal of Antimicrobial Chemotherapy·Carla Andrea AlonsoStefan Schwarz
Jul 27, 2017·Journal of Global Antimicrobial Resistance·S H M P WimalasenaGang-Joon Heo
Feb 9, 2018·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Sabrina HossainGang-Joon Heo

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