Multidrug-resistant bacteria colonization amongst patients newly admitted to a geriatric unit: a prospective cohort study

The Journal of Infection
Didier SchoevaerdtsYouri Glupczynski

Abstract

To determine prevalence, incidence and risk factors of colonization by extended-spectrum β-lactamase-producing Enterobacteriacae (ESBLE), methicillin-resistant Staphylococcus aureus (MRSA), and vancomycin-resistant Enterococcus (VRE) in aged subjects admitted to an acute geriatric unit at a teaching hospital. During 12 months, 337 patients were screened by nasal, oropharyngeal, groin, axillary and rectal swabs upon admission and at discharge. The prevalence of ESBLE, MRSA and VRE carriage upon admission was 11.6%, 7.5% and 0.6%, respectively. The incidence density of ESBLE and MRSA carriage was respectively of 1.77 and 2.40 new cases for 1000 patient-days. No cases of VRE acquisition were found. Risk factors for ESBLE colonization on admission were: multiple contacts with the hospital within the previous year, chronic catheter use and a high level of dependency. For MRSA, risk factors were: chronic wounds, anti-acid use and a high level of dependency. This study shows a high prevalence of asymptomatic colonization of ESBL-producing Escherichia coli in patients admitted to an acute geriatric ward, as high as MRSA carriage. A low functional status is a common risk factor both for ESBLE and for MRSA colonization and it highlights ...Continue Reading

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Citations

Dec 20, 2015·Virulence·Dafna YahavMical Paul
Jan 7, 2014·American Journal of Infection Control·Mouna TarchounaJalel Boukadida
Apr 10, 2013·The American Journal of Cardiology·Robert M A van der BoonPeter P T de Jaegere
Feb 1, 2015·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C L BeckettB Huttner
Aug 25, 2015·American Journal of Infection Control·Sachi MatsubayashiKayoko Hayakawa
Sep 4, 2012·Archives of Gerontology and Geriatrics·Didier SchoevaerdtsYouri Glupczynski
Apr 30, 2014·American Journal of Infection Control·Sameen FarooqKeith S Kaye
Oct 5, 2013·Clinical Microbiology Reviews·Paul-Louis WoertherAntoine Andremont
Dec 8, 2017·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Marjolein F Q Kluytmans-van den BerghUNKNOWN SoM Study Group and the R-GNOSIS Study Group
Aug 21, 2020·The Journal of Antimicrobial Chemotherapy·Nasra DuallehIsik Somuncu Johansen
Oct 28, 2019·Aging Clinical and Experimental Research·Didier SchoevaerdtsGaetan Gavazzi

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