Multidrug-Resistant Bacterial Infections in Solid Organ Transplant Candidates and Recipients

Infectious Disease Clinics of North America
Michele BartolettiPierluigi Viale

Abstract

The current era is ruled by an alarming evolution of antimicrobial resistance. Solid organ transplant recipients are prone to develop infections caused by multidrug-resistant pathogens. The current challenges in this setting include screening of donors and recipients, and prevention/treatment of donor-derived and posttransplant infections. The epidemiology of these infections varies between centers, type of transplanted organ, and pathogen. Treatment options are limited. Efforts to reduce carbapenem antibiotic pressure and infection control measures are necessary to reverse the spread of multidrug-resistant pathogens. Novel drugs for gram-negative multidrug-resistant bacilli may contribute to reduce carbapenemase diffusion and reduce the rate of treatment failure.

Citations

Nov 30, 2019·Expert Opinion on Drug Discovery·Suresh MaddilaSreekantha B Jonnalagadda
Jan 1, 2020·American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons·Elena Pérez-NadalesUNKNOWN REIPI/INCREMENT-SOT Investigators
Jul 14, 2020·Current Opinion in Infectious Diseases·Saima Aslam
Nov 9, 2020·Antimicrobial Resistance and Infection Control·Carlos L Correa-MartínezStefanie Kampmeier
Nov 21, 2020·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Kelly A CairnsAnton Y Peleg

Jan 5, 2021·Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
Feb 3, 2021·Pediatric Transplantation·Taito KitanoAaron Campigotto
Feb 4, 2021·The Journal of Antimicrobial Chemotherapy·Maddalena GiannellaElda Righi
Sep 22, 2021·CA: a Cancer Journal for Clinicians·Amila K NanayakkaraDavid E Greenberg
May 31, 2019·Current Opinion in Organ Transplantation·Jonathan Hand, Gopi Patel
Jun 7, 2019·Current Opinion in Organ Transplantation·Darren Wong, David van Duin

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Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

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Carbapenems are members of the beta lactam class of antibiotics and are used for the treatment of severe or high-risk bacterial infections. Discover the latest research on carbapenems here.

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