Multidrug-resistant high-risk Enterococcus faecium clones: can we really define them?

International Journal of Antimicrobial Agents
Ana R FreitasLuísa Peixe

Abstract

Enterococcus faecium is a significant opportunistic human pathogen with a broad host range, including humans, farm animals, pets and wildlife. Specialised subpopulations have globally evolved towards a powerful and convergent adaption to the healthcare environment by acquiring a cocktail of key antimicrobial resistance and virulence genes, enabling them to thrive in the disturbed microbiota of hospitalised patients. These populations can also be found in different community reservoirs, but the relevance of their dispersal in non-human hosts is greatly unknown and is here discussed. This review provides a brief historical overview of what we have been considering E. faecium high-risk clones worldwide alongside the advances in strain typing technologies that have revolutionised our understanding of the genetic evolution of this species over the last three decades.

References

Aug 19, 2000·The Journal of Infectious Diseases·R J WillemsJ D van Embden
May 21, 2004·Nature Reviews. Microbiology·Fernando Baquero
Jun 21, 2005·Emerging Infectious Diseases·Rob J L WillemsMarc J M Bonten
Aug 2, 2006·Current Opinion in Microbiology·Helen L LeavisRob J L Willems
Sep 4, 2008·The Journal of Antimicrobial Chemotherapy·Camilla H LesterUNKNOWN DANRES Study Group
Feb 24, 2009·Applied and Environmental Microbiology·Peter DamborgLuca Guardabassi
Jun 24, 2010·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C A AriasB E Murray
Mar 17, 2012·Nature Reviews. Microbiology·Cesar A Arias, Barbara E Murray
Apr 11, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·A M Hammerum
Mar 1, 2013·The Journal of Infectious Diseases·Sudha R Somarajan, Barbara E Murray
Aug 15, 2013·MBio·Benjamin P HowdenTimothy P Stinear
Dec 17, 2015·The Journal of Infectious Diseases·Maria Camila MontealegreBarbara E Murray
May 18, 2016·International Journal of Antimicrobial Agents·Ana R FreitasLuísa Peixe
Jun 16, 2016·Frontiers in Microbiology·Ana M Guzman PrietoRob J L Willems
Sep 23, 2016·The Journal of Antimicrobial Chemotherapy·Ana P TedimTeresa M Coque
May 16, 2017·Cell·François LebretonMichael S Gilmore
Nov 18, 2017·The Journal of Antimicrobial Chemotherapy·Ana R FreitasLuísa Peixe
Dec 12, 2017·Current Opinion in Microbiology·Wei GaoTimothy P Stinear
Aug 3, 2018·Science Translational Medicine·Sacha J PidotTimothy P Stinear
Oct 1, 2018·American Journal of Infection Control·Sarah S JacksonUNKNOWN CDC Prevention Epicenters Program
Nov 18, 2018·Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy·Jennifer K BenderGuido Werner
Jan 17, 2019·The Journal of Antimicrobial Chemotherapy·Gianluca MorroniFrancesca Biavasco
Feb 1, 2019·Clinical Microbiology Reviews·Mónica García-Solache, Louis B Rice
Mar 22, 2019·The Journal of Antimicrobial Chemotherapy·Mohamed SassiVincent Cattoir
Apr 23, 2019·The Journal of Antimicrobial Chemotherapy·Costas C PapagiannitsisEfi Petinaki
Aug 7, 2019·Antimicrobial Resistance and Infection Control·Linda FalgenhauerTrinad Chakraborty
Sep 29, 2019·Applied and Environmental Microbiology·Bárbara DuarteCarla Novais
Jan 3, 2020·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Jennifer K BenderGuido Werner

❮ Previous
Next ❯

Citations

May 18, 2021·The Science of the Total Environment·Andreia RebeloUNKNOWN from the ESCMID Study Group on Food- and Water-borne Infections (EFWISG)
Jun 20, 2021·International Journal of Food Microbiology·Liliana FinisterraAna R Freitas
Aug 18, 2021·International Journal of Systematic and Evolutionary Microbiology·Mireya Viviana Belloso DazaPier Sandro Cocconcelli

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Advances in Experimental Medicine and Biology
D MorrisonB D Cookson
The Journal of Infectious Diseases
Jenna I WursterMichael S Gilmore
Archives of Disease in Childhood. Fetal and Neonatal Edition
D P BarkerM R Millar
© 2021 Meta ULC. All rights reserved