Multidrug-resistant Mycobacterium tuberculosis and associated risk factors in Oromia Region of Ethiopia

International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases
Girma MulisaGodana Jarso

Abstract

The aim of this study was to determine risk factors for tuberculosis (TB) caused by multidrug-resistant Mycobacterium tuberculosis (MDR-TB) in Oromia Region, Ethiopia. A 6-month case-control study was performed in 2013-14. Sputum samples and standardized questionnaire data (demographics, treatment, TB contact history, underlying disease, history of imprisonment) were collected from cases with suspected MDR-TB aged ≥ 18 years. Sputum was processed locally in the Oromia Public Health Laboratory using standard techniques. Data from MDR-TB cases and TB-positive controls were compared using logistic regression analysis. For each factor, the association with outcome variables was estimated by calculating the odds ratio (OR) together with the 95% confidence interval (95% CI). Of 439 suspected MDR-TB cases, 265 had a confirmed M. tuberculosis infection, of whom 88 (33%) had laboratory-confirmed MDR-TB. Over two-thirds (65%) were between 18 and 39 years of age. On multivariate analysis, an occupation of farming, known TB contact history, alcohol use, HIV infection, previous known TB history, and previous TB treatment outcome were predictors of MDR-TB. The rate of MDR-TB was high among suspected cases in the Oromia Region of Ethiopia. Lo...Continue Reading

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Citations

Oct 27, 2016·BMC Infectious Diseases·Thilini Piushani KeerthirathneSuneth Sithumini Sooriyapathirana
Oct 14, 2017·Health Policy and Planning·Mishal S KhanSithu Aung
Jul 15, 2017·The European Respiratory Journal·Mario Raviglione, Vladimir Poznyak
Mar 12, 2020·Infection and Drug Resistance·Hadush NegashBrhane Berhe
Dec 20, 2018·BMC Infectious Diseases·Mebrahtu TeweldemedhinSolomon Weldegebreal Asgedom
Oct 5, 2019·The Canadian Journal of Infectious Diseases & Medical Microbiology = Journal Canadien Des Maladies Infectieuses Et De La Microbiologie Médicale·Kibriti MehariMuthupandian Saravanan
Jun 1, 2018·Journal of Pathogens·Solomon Weldegebreal AsgedomHailay Gebreyesus
Jul 5, 2018·Annals of Clinical Microbiology and Antimicrobials·Dabesa GobenaTessema Debela
Dec 21, 2018·Revista da Escola de Enfermagem da U S P·Kuitéria Ribeiro FerreiraAmy Bender
Oct 20, 2019·Respiratory Research·Wan-Mei SongHuai-Chen Li
Dec 1, 2019·BMC Pulmonary Medicine·Mulusew Andualem AsemahagnSolomon Abebe Yimer
Jul 2, 2020·Infection and Drug Resistance·Daniel Biru, Endrias Markos Woldesemayat
Jul 22, 2019·Antibiotics·Monadil H AliBrian Godman
Nov 16, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Mebrat EjoBouke C de Jong
Jan 13, 2021·BMC Infectious Diseases·Zeeba Zahra SultanaAhmed Hossain
Mar 13, 2021·BMC Public Health·Lesley-Ann Lynnath CannonDaniel Ter Goon
Jun 12, 2021·Infection and Drug Resistance·Mohammed Hasen Bedaso, Falaho Sani Kalil
Sep 2, 2021·Journal of Research in Health Sciences·Teramaj Wongel WotaleJaleta Abdisa Fufa
Nov 7, 2021·Transboundary and Emerging Diseases·Ayinalem AlemuBalako Gumi

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