PMID: 11917817Mar 29, 2002Paper

Multidrug-resistant tuberculosis

Infectious Disease Clinics of North America
Barbara J Seaworth

Abstract

Multidrug-resistant TB is a growing public health problem. Although control of the multidrug-resistant TB epidemic has been achieved in New York City, strains of multidrug-resistant TB are found in nearly every state. Much of the world faces a growing problem with no immediate solution. The treatment habits and policies that have led to this problem persist. New drug development has been almost nonexistent. The current tremendous global interest offers hope, as does the Global Alliance for Tuberculosis Drug Development supported by the Rockefeller Foundation and the Bill and Melinda Gates Foundation. Their mission is to accelerate the discovery and development of new antituberculosis drugs and put them on the market within 10 years, at prices affordable in less-developed countries. As Dr. Reichman notes, "this action will not address the main underlying cause of almost all drug resistance, non-adherence of patients and doctors to recommended regimens." He calls for an equal commitment to improving the capacity of health care workers to use new and older agents correctly, so that they may continue to be effective in the future. Each year brings new, at-risk immigrants to the United States from all regions of the globe. They brin...Continue Reading

Citations

Jul 20, 2002·Current Infectious Disease Reports·Scott W. Sinner, Allan R. Tunkel
Apr 4, 2006·Current Opinion in Pulmonary Medicine·Umesh G LallooAnish Ambaram
Oct 23, 2003·Southern Medical Journal·Ronald C Hamdy
Dec 19, 2009·American Journal of Therapeutics·Parvaneh BaghaeiAliakbar Velayati
Jan 27, 2004·American Journal of Respiratory and Critical Care Medicine·Edward D ChanMichael D Iseman
Nov 26, 2005·Expert Review of Anti-infective Therapy·Kim Connelly Smith, Barbara J Seaworth
Apr 12, 2003·Current Opinion in Pulmonary Medicine·Ivan BastianRobert Colebunders
Dec 12, 2003·Nature Reviews. Drug Discovery·Solomon Nwaka, Robert G Ridley
Nov 28, 2008·Scandinavian Journal of Infectious Diseases·Payam TabarsiAli A Velayati
Nov 16, 2019·American Journal of Respiratory and Critical Care Medicine·Payam NahidBarbara Seaworth
Aug 24, 2013·Revista Da Sociedade Brasileira De Medicina Tropical·Bruno Horta AndradeRicardo de Amorim Côrrea
Nov 19, 2010·Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia·Marcos Abdo ArbexFernando Augusto Fiúza de Mello
Jul 13, 2005·Journal of Microbiological Methods·Y AkselbandP McGrath
Mar 4, 2006·Science·Seth W GlickmanKevin A Schulman

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