Multiecho imaging with suboptimal spoiler gradients

Journal of Magnetic Resonance
Mark D Does, R E Snyder

Abstract

Although multiecho imaging may be used to measure transverse relaxation (T2), B1 and B0 inhomogeneity generally gives rise to unwanted coherence pathway signals which result in erroneous T2 measurements. One approach to suppressing this unwanted signal is to center each rf refocusing pulse between spoiler gradients which dephase the unwanted signal; however, hardware limitations often dictate the use of suboptimal spoiler gradients, that is, gradients that cannot provide sufficient dephasing strength. Using simulations, this work demonstrates that by means of a small additional spoiler gradient prior to the first rf refocusing pulse it is possible to reduce substantially the contribution from unwanted coherence pathways in multiecho imaging studies that use suboptimal spoiler gradients. This reduction of unwanted signal results in measured T2 values within approximately 1% of values obtained using spoiler gradients of optimal strength. These results were found for a wide range of biologically relevant T1 and T2 values, missettings of the rf refocusing pulse as large as 5%, and frequency offsets of up to 25 Hz. Multiecho image data agreed with the simulations. Using the additional spoiler gradient it is possible to reduce spoile...Continue Reading

Citations

May 17, 2005·Radiologic Clinics of North America·Christian Glaser
Mar 14, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christopher L Lankford, Mark D Does
Nov 21, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Chuan HuangMaria I Altbach
Jan 18, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Md Nasir UddinAlan H Wilman
Jun 22, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·R Marc Lebel, Alan H Wilman
Jun 19, 2013·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Henry S ChenPiotr Kozlowski
Apr 19, 2015·Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance·Tomoe HagioMaria I Altbach
Apr 21, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Christopher L Lankford, Mark D Does
Feb 11, 2000·NMR in Biomedicine·M D Does, J C Gore
Apr 26, 2001·NMR in Biomedicine·F R FenrichP S Allen

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