Multifarious injection chamber for molecular structure study (MICOSS) system: development and application for serial femtosecond crystallography at Pohang Accelerator Laboratory X-ray Free-Electron Laser

Journal of Synchrotron Radiation
Jaehyun ParkKi Hyun Nam

Abstract

The multifarious injection chamber for molecular structure study (MICOSS) experimental system has been developed at the Pohang Accelerator Laboratory X-ray Free-Electron Laser for conducting serial femtosecond crystallography. This system comprises several instruments such as a dedicated sample chamber, sample injectors, sample environment diagnostic system and detector stage for convenient distance manipulation. Serial femtosecond crystallography experiments of lysozyme crystals have been conducted successfully. The diffraction peaks have reached to ∼1.8 Å resolution at the photon energy of 9.785 keV.

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Citations

Mar 2, 2019·Acta Crystallographica. Section D, Structural Biology·Isabelle MartielAina E Cohen
Jun 12, 2019·Expert Opinion on Drug Discovery·Alexey MishinVadim Cherezov
Apr 14, 2020·Journal of Applied Crystallography·Donghyeon LeeJaehyun Park
Apr 24, 2019·International Journal of Molecular Sciences·Jae-Hyun ParkWeontae Lee
Feb 23, 2019·Scientific Reports·Jaehyun ParkKi Hyun Nam

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