Multifetal pregnancy reduction: a review of the world results for the period 1993-1996

European Journal of Obstetrics, Gynecology, and Reproductive Biology
S J Fasouliotis, J G Schenker

Abstract

The objective of this work was to evaluate the outcome of multifetal pregnancy reduction and to provide an analysis of the ethical dilemmas associated with its application. The study design was based on data on over 1400 completed pregnancies that underwent multifetal pregnancy reduction as reported in the world literature during 1993-1996. The results were: A total of 1453 completed cases of multifetal pregnancy reduction are presented. The total survival rate was estimated to be 87.7%, resulting in a total pregnancy loss rate of 12.3%. The lowest survival rate is found to be in higher-order pregnancies of five or more fetuses (75.2%), whereas pregnancy loss rate seems to be similar for quadruplets, triplets and twins that underwent reduction (11.3%, 8.3% and 13.6%, respectively). A 33.3% of the total pregnancy loss rate occurred within four weeks from the procedure, whereas 66.7% occurred after the four weeks but at 24 weeks of gestation or earlier. The mean gestational age at delivery was estimated to be 33 weeks for pregnancies reduced to triplets, 35.8 weeks for those reduced to twins and 36.9 weeks for singletons, with 5% delivering at less than 28 weeks and 9.6% at 29-32 weeks. We conclude that multifetal pregnancy reduc...Continue Reading

References

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Citations

May 29, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·S J Fasouliotis, J G Schenker
Feb 21, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Sozos J Fasouliotis, Joseph G Schenker
Apr 2, 2014·Seminars in Fetal & Neonatal Medicine·S R Murray, J E Norman
Feb 12, 2000·Public Health Reports·A T Fidler, J Bernstein
Feb 12, 2005·Fertility and Sterility·Apostolos P AlphathanasiadisJohn Bontis
Jan 1, 2013·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Rong LiJie Qiao
Feb 24, 2000·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·S J Fasouliotis, J G Schenker

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