Multifocal noninfectious granulomatous encephalitis in a child. Case report

Journal of Neurosurgery
T M LasnerL B Rorke

Abstract

This 9-year-old boy presented with a multifocal, apparently noninfectious granulomatous process involving the central nervous system. Despite gross-total excision of the large left temporal lesion, it recurred after surgery. Serological studies and cultures failed to demonstrate an infectious agent, and histopathological investigation showed a nonspecific granulomatous process without vasculitis. The patient underwent a second craniotomy and was given corticosteroid therapy. There has been no recurrence during 3 years of follow-up review, the last year of which included no course of steroid medications. The case is presented as a noninfectious idiopathic granulomatous encephalitis that is responsive to surgery and corticosteroid therapy. To the authors' knowledge, it is the first reported case of its kind.

References

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Citations

Mar 19, 2002·Pediatric Neurology·Marcelo GalarzaJorge A Monges
Dec 16, 2003·Current Opinion in Rheumatology·Susanne Benseler, Rayfel Schneider
Nov 10, 2006·Current Rheumatology Reports·Susanne M Benseler
Sep 26, 2006·Pediatric Neurology·Avinoam ShuperLucy B Rorke-Adams

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Methods Mentioned

BETA
electrophoresis
biopsy

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