Multifocal plasmacytoma of hand and foot bones

Leukemia & Lymphoma
N AntonijevićZ Rolović

Abstract

Simultaneous occurrence of localized plasmacytomas of both hands and feet has not been reported so far. Here we report a 40-year old female patient, who had at presentation pain and deformity. Of hands and feet, with numerous cystic lytic lesions of phalangeal, metacarpal and metatarsal bones, detected by X-rays. The biopsy of the affected bone showed moderately differentiated plasmacytoma of lambda light chain type (lambda-LC). Serum and urine biochemical analysis revealed the existence of lambda LC monoclonal component. The patient was treated by local radiotherapy and subsequent systemic chemotherapy, which consisted of 3 cycles of the M-2 protocol and 7 cycles of melphalan-prednisone. Five years after the diagnosis, the absence of plasmacytoma was confirmed by puncture biopsy of the left hand phalanx. Monoclonal protein in serum and urine was not detected.

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Citations

Jun 26, 2014·Journal of Clinical Pathology·Yahya DaneshbodL Jeffrey Medeiros
Sep 30, 2017·Scottish Medical Journal·Esra YildizhanBulent Eser
Mar 14, 2007·Clinical Orthopaedics and Related Research·Deep S ChathaPanna Desai

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