Multifunctional agents for concurrent imaging and therapy in cardiovascular disease.

Advanced Drug Delivery Reviews
Jason R McCarthy

Abstract

The development of agents for the simultaneous detection and treatment of disease has recently gained significant attention. These multifunctional theranostic agents posses a number of advantages over their monofunctional counterparts, as they potentially allow for the concomitant determination of agent localization, release, and efficacy. Whereas the development of these agents for use in cancers has received the majority of the attention, their use in cardiovascular disease is steadily increasing. As such, this review summarized some of the most poignant recent advances in the development of theranostic agents for the treatment of this class of diseases.

References

Dec 14, 1995·The New England Journal of Medicine·UNKNOWN National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
Dec 20, 2002·Nature·Peter Libby
Jan 28, 2004·Circulation·Jaikirshan J KhatriZorina S Galis
Jan 18, 2005·Circulation Research·Kimberly A KellyRalph Weissleder
Apr 22, 2005·The New England Journal of Medicine·Göran K Hansson
Oct 6, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Willem J M MulderKlaas Nicolay
Jun 17, 2006·Nature Reviews. Immunology·Göran K Hansson, Peter Libby
Aug 5, 2006·Thrombosis Research·Susan D Tiukinhoy-LaingDavid D McPherson
Dec 29, 2006·Small·Jason R McCarthyRalph Weissleder
May 17, 2007·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Timothy BrightonS Patrick Butler
Aug 25, 2007·Nanomedicine·Jason R McCarthyRalph Weissleder
Aug 25, 2007·Nanomedicine·Gregory M LanzaSamuel A Wickline
Aug 29, 2007·Circulation·Farouc A JafferRalph Weissleder
Dec 26, 2007·Circulation·Matthias NahrendorfRalph Weissleder
May 24, 2008·Nature Reviews. Cancer·Christie J AvraamidesJudith A Varner
May 30, 2008·Advanced Drug Delivery Reviews·Jason R McCarthy, Ralph Weissleder
Aug 30, 2008·The New England Journal of Medicine·Bruce Furie, Barbara C Furie
Apr 10, 2009·JACC. Cardiovascular Imaging·Patrick M WinterGregory M Lanza
May 16, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Fabien HyafilZahi A Fayad
Jun 3, 2009·Proceedings of the National Academy of Sciences of the United States of America·David PetersErkki Ruoslahti
Nov 11, 2009·Ultrasound in Medicine & Biology·Denise A B SmithChristy K Holland
Nov 17, 2009·ACS Nano·Angana SenpanGregory M Lanza

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Citations

Dec 10, 2013·Analytical Chemistry·Niall CrawleyAlexander Romaschin
Aug 13, 2011·Bioconjugate Chemistry·Sneha S Kelkar, Theresa M Reineke
Sep 14, 2011·Journal of the American Chemical Society·Santimukul SantraJ Manuel Perez
Jul 28, 2012·Therapeutic Delivery·Tatyana S LevchenkoVladimir P Torchilin
Nov 8, 2011·Therapeutic Delivery·Brian E O'Neill, Natalya Rapoport
Mar 7, 2014·Pharmaceutical Research·Dan WangHua Ai
Mar 22, 2014·International Journal of Nanomedicine·Xiaomin YiJianlin Yuan
Oct 1, 2013·Drug Delivery and Translational Research·Udita AgrawalS P Vyas
Dec 19, 2014·Marine Drugs·Jin-Kyu RheeKyeongsoon Park
Jan 13, 2012·Expert Opinion on Drug Delivery·Kristen BoweyMaryam Tabrizian
Aug 30, 2012·Ultrasound in Medicine & Biology·Kirthi RadhakrishnanChristy K Holland
Nov 3, 2015·International Journal of Pharmaceutics·Muhammad IqbalAbdelhamid Elaissari
May 9, 2014·Biomaterials·Keum-Young AhnJeewon Lee
May 24, 2011·Nanomedicine : Nanotechnology, Biology, and Medicine·Anirban Sen Gupta
Aug 5, 2014·ACS Applied Materials & Interfaces·Yongyi ZengXiaolong Liu
Sep 7, 2016·Advanced Drug Delivery Reviews·Benjamin M LubyGang Zheng
Sep 26, 2016·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Moumita Roy ChowdhuryGunjan Guha
Mar 13, 2018·Drug Development and Industrial Pharmacy·Lorenzo Degli EspostiMichele Iafisco
Sep 17, 2014·Dalton Transactions : an International Journal of Inorganic Chemistry·Sasmita MohapatraTapas K Maiti
Nov 14, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Linlin ZhaoSo Yeon Kim
Dec 16, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Samira JafariAli Akbar Saboury
Mar 24, 2021·Journal of Nanobiotechnology·Xiajing ChenJie Tian
Sep 30, 2020·Journal of Medicinal Chemistry·João C S SimõesGeorge Loudos
Jul 6, 2021·Current Pharmaceutical Design·Rakesh K SahooAmit K Goyal

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