Multifunctional cytotoxic agents from Anacardium occidentale

Phytotherapy Research : PTR
Isao KuboIvan R Green

Abstract

The effects of anacardic acids and cardols isolated from the cashew nut and apple Anacardium occidentale (Anacardiaceae) on murine B16-F10 melanoma cells were tested. Although anacardic acids and cardols were found to inhibit tyrosinase, a key enzyme in melanin synthesis, melanogenesis in melanocytes was not suppressed in cultured cells but rather enhanced. Both anacardic acids and cardols exhibited moderate cytotoxicity.

References

Jan 1, 1992·CA: a Cancer Journal for Clinicians·C C BoringT Tong
Apr 1, 1994·Journal of Natural Products·I KuboY Yokokawa
Jul 1, 1996·CA: a Cancer Journal for Clinicians·D L Morton, A Barth
Oct 1, 1995·Journal of Lipid Mediators and Cell Signalling·D Shibata, B Axelrod
Aug 1, 1997·The Journal of Biological Chemistry·E S Henle, S Linn
Sep 23, 1998·Carcinogenesis·N Rioux, A Castonguay
Dec 16, 1998·The British Journal of Nutrition·A T DiplockJ Viña-Ribes
Nov 25, 2003·Fitoterapia·Angela I ReaEphraim T Gwebu
Dec 11, 2003·Journal of Agricultural and Food Chemistry·Isao KuboKazuo Tsujimoto
Mar 31, 2004·Bioorganic & Medicinal Chemistry·Radhakrishnan VenkatasamyRobert C Hider
Apr 6, 2004·Biochimica Et Biophysica Acta·Noriyoshi Masuoka, Isao Kubo
Apr 7, 2004·The Journal of Biological Chemistry·Akiko KageyamaChikako Nishigori
May 26, 2005·Journal of Agricultural and Food Chemistry·Tae Joung Ha, Isao Kubo
Aug 13, 2005·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·M T S TrevisanR W Owen
Sep 10, 2005·Colloids and Surfaces. B, Biointerfaces·Liang PengPeng Ren
Jun 5, 2007·Zeitschrift Für Naturforschung. C, a Journal of Biosciences·Sadaaki TamuraIsao Kubo

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Citations

Mar 31, 2012·BMC Complementary and Alternative Medicine·Dungporn TeerasripreechaChanpen Chanchao
Aug 25, 2015·Environmental Research·Carlos L CespedesDavid S Seigler
Mar 3, 2012·Journal of Enzyme Inhibition and Medicinal Chemistry·Joonseok OhMinKyun Na
Aug 10, 2019·Natural Product Research·Abdullahi ShehuGabriel Ademola Olatunji
Oct 6, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Paula M KustiawanChanpen Chanchao
Sep 15, 2017·Evidence-based Complementary and Alternative Medicine : ECAM·Natália Cabral SouzaMatheus Augusto de Bittencourt Pasquali
Nov 23, 2011·Basic & Clinical Pharmacology & Toxicology·Mahadevappa HemshekharKesturu S Girish
Jun 3, 2021·Cancers·Ruicen HeKarl Riabowol
Dec 10, 2016·Journal of Agricultural and Food Chemistry·Tavane A AlvarengaPatrícia M Pauletti

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