Multigeneration assessment of nonylphenol and endosulfan using a model Australian freshwater fish, Melanotaenia fluviatilis

Environmental Toxicology
Douglas A HoldwayAnna Smith

Abstract

Changes over two generations in offspring and reproductive ability were recorded in crimson-spotted rainbowfish (Melanotaenia fluviatilis), a model Australasian freshwater fish, following a 24 h exposure to nominal nonylphenol concentrations of 50, 100, 500, 1000, 2250, and 5000 microg/L and following a 4 h exposure to nominal endosulfan concentrations of 1.0, 5.0, 10, 22, 33, and 50 microg/L. There were also four replicated control treatments: control 1 and 2 and solvent control 1 and 2, as well as "positive" female and male controls: 1 microg/L estradiol 1 and 2 and 1 microg/L testosterone 1 and 2. Results suggested that there may be some parental transfer of toxicants to embryos even over this short exposure period. Fertility of M. fluviatilis was reduced by a 24 h pulse exposure of adults to 100 microg/L nonylphenol and a 4 h exposure to 1.0 microg/L endosulfan. Hatch rates were significantly reduced after exposure to nonylphenol, endosulfan, and estradiol control but not in solvent controls and testosterone control. Significant correlations were found between reproductive and physiological parameters for nonylphenol and endosulfan exposed F0 adult rainbowfish. The major reproductive effects were on hatchability of the F1 g...Continue Reading

References

Jun 1, 1994·Ecotoxicology and Environmental Safety·R Kvestak, M Ahel
Dec 1, 1996·Risk Analysis : an Official Publication of the Society for Risk Analysis·R J Kavlock, G T Ankley
Aug 12, 1998·The Journal of Steroid Biochemistry and Molecular Biology·C Sonnenschein, A M Soto
Feb 24, 1999·The Science of the Total Environment·D E Kime
Mar 3, 1999·Ecotoxicology and Environmental Safety·A W LeonardJ C Chapman
Jul 3, 2002·Water Research·Shosaku KashiwadaYasumoto Magara
Sep 12, 2002·Environment International·Guang-Guo YingRai Kookana
Apr 11, 2003·Chemosphere·Spyros K GolfinopoulosDimitris T Lekkas
May 23, 2007·Proceedings of the National Academy of Sciences of the United States of America·Karen A KiddRobert W Flick

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Citations

May 18, 2013·The Science of the Total Environment·Ming-Song TsaiMei-Lien Chen
Oct 28, 2015·Environmental Toxicology and Chemistry·Bruno CamposCarlos Barata

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