Multileaf collimator tongue-and-groove effect on depth and off-axis doses: a comparison of treatment planning data with measurements and Monte Carlo calculations

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
Hee Jung KimSung-Joon Ye

Abstract

To investigate how accurately treatment planning systems (TPSs) account for the tongue-and-groove (TG) effect, Monte Carlo (MC) simulations and radiochromic film (RCF) measurements were performed for comparison with TPS results. Two commercial TPSs computed the TG effect for Varian Millennium 120 multileaf collimator (MLC). The TG effect on off-axis dose profile at 3 depths of solid water was estimated as the maximum depth and the full width at half maximum (FWHM) of the dose dip at an interleaf position. When compared with the off-axis dose of open field, the maximum depth of the dose dip for MC and RCF ranged from 10.1% to 20.6%; the maximum depth of the dose dip gradually decreased by up to 8.7% with increasing depths of 1.5 to 10cm and also by up to 4.1% with increasing off-axis distances of 0 to 13cm. However, TPS results showed at most a 2.7% decrease for the same depth range and a negligible variation for the same off-axis distances. The FWHM of the dose dip was approximately 0.19cm for MC and 0.17cm for RCF, but 0.30cm for Eclipse TPS and 0.45cm for Pinnacle TPS. Accordingly, the integrated value of TG dose dip for TPS was larger than that for MC and RCF and almost invariant along the depths and off-axis distances. We c...Continue Reading

References

Dec 1, 1995·International Journal of Radiation Oncology, Biology, Physics·E E KleinJ A Purdy
May 1, 1995·Medical Physics·D W RogersT R Mackie
Oct 1, 1996·Physics in Medicine and Biology·J P van Santvoort, B J Heijmen
Nov 14, 1998·Physics in Medicine and Biology·J R Sykes, P C Williams
Apr 28, 2001·Physics in Medicine and Biology·J DengC M Ma
Oct 24, 2001·Zeitschrift für medizinische Physik·M K FixP Rüegsegger
Jun 19, 2002·Physics in Medicine and Biology·C M MaS Brain
Oct 4, 2002·Physics in Medicine and Biology·Jeffrey V SiebersRadhe Mohan
Jun 9, 2005·Journal of Applied Clinical Medical Physics·Patrick CadmanKarl Bzdusek
Mar 15, 2006·Medical Physics·Falk PönischRadhe Mohan
May 2, 2008·Journal of Applied Clinical Medical Physics·Gareth J WebsterRanald I Mackay
Apr 28, 2011·Medical Physics·Daniel A LowMark Oldham
Oct 14, 2011·Medical Physics·Michael K FixPeter Manser

❮ Previous
Next ❯

Citations

Jan 20, 2021·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Kengo IwakiNoriko Ii

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.