Multilevel BCR signals toward CLL.

Blood
Marco Herling, Elena Vasyutina

Abstract

In this issue of Blood, Iacovelli et al provide the first in vivo experimental evidence on the proleukemogenic relevance of autonomous (exo-antigen–independent) B-cell receptor (BCR) stimulation in conjunction with ligand (autoantigen)- mediated BCR signaling in chronic lymphocytic leukemia (CLL).

References

Jul 26, 2006·Proceedings of the National Academy of Sciences of the United States of America·Xiao-jie YanNicholas Chiorazzi
Oct 24, 2012·The Journal of Experimental Medicine·Marc SeifertRalf Küppers
Aug 10, 2013·Trends in Immunology·Jan A Burger, Nicholas Chiorazzi

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