Multilevel meta-analysis of multiple regression coefficients from single-case experimental studies

Behavior Research Methods
Laleh JamshidiWim Van den Noortgate

Abstract

The focus of the current study is on handling the dependence among multiple regression coefficients representing the treatment effects when meta-analyzing data from single-case experimental studies. We compare the results when applying three different multilevel meta-analytic models (i.e., a univariate multilevel model avoiding the dependence, a multivariate multilevel model ignoring covariance at higher levels, and a multivariate multilevel model modeling the existing covariance) to deal with the dependent effect sizes. The results indicate better estimates of the overall treatment effects and variance components when a multivariate multilevel model is applied, independent of modeling or ignoring the existing covariance. These findings confirm the robustness of multilevel modeling to misspecifying the existing covariance at the case and study level in terms of estimating the overall treatment effects and variance components. The results also show that the overall treatment effect estimates are unbiased regardless of the underlying model, but the between-case and between-study variance components are biased in certain conditions. In addition, the between-study variance estimates are particularly biased when the number of studie...Continue Reading

References

Jan 11, 1984·The Journal of Applied Behavioral Science·W J Gingerich
May 2, 2003·Behavior Research Methods, Instruments, & Computers : a Journal of the Psychonomic Society, Inc·Wim Van den Noortgate, Patrick Onghena
Mar 5, 2004·Behavior Modification·Jonathan M Campbell
Dec 16, 2004·The Clinical Journal of Pain·Patrick Onghena, Eugene S Edgington
Mar 18, 2011·Behavior Modification·Richard I ParkerJohn L Davis
Jun 10, 2011·Behavior Research Methods·William R Shadish, Kristynn J Sullivan
Dec 20, 2011·Behavior Research Methods·Corina M Owens, John M Ferron
Jun 1, 2012·Behavior Research Methods·Maaike UgilleWim Van den Noortgate
Oct 12, 2012·Behavior Research Methods·Wim Van den NoortgateJulio Sánchez-Meca
Jan 1, 2010·Research Synthesis Methods·Larry V HedgesMatthew C Johnson
Sep 1, 2013·Multivariate Behavioral Research·Mariola MoeyaertWim Van den Noortgate
Jan 13, 2017·Behavior Therapy·Rumen Manolov, Mariola Moeyaert

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.