Multiloculated solitary (unicameral) bone cyst in a young dog

Veterinary Clinical Pathology
Sarah C RoodeCarol B Grindem

Abstract

A 20-month-old female spayed Staffordshire Terrier (22.3 kg) presented to the Orthopedic Surgery Service at North Carolina State University Veterinary Teaching Hospital for evaluation of a 6-week history of toe-touching to nonweight-bearing lameness in the right hind limb. Radiographs of the right stifle revealed a multiloculated lytic lesion of the distal femur, with a large open lytic zone centrally, numerous osseous septations peripherally, and focal areas of cortical thinning and loss. An aspirate of the right distal femoral lesion yielded mildly cloudy serosanguineous fluid. Cytologic examination of the fluid revealed a pleomorphic population of discrete cells that exhibited marked anisocytosis and anisokaryosis and a variable nuclear-to-cytoplasmic (N:C) ratio, which were interpreted as probable neoplastic cells, with few macrophages, and evidence of hemorrhage. Given the clinical signs of pain, lesion size, and concern for malignant neoplasia, amputation of the right hind limb was performed. Histologically, the lesion had undulating walls 1-3 mm thick with a continuous outer layer of dense fibrous tissue and an inner layer composed of reactive cancellous bone with no cortical compacta remaining. Remnants of thin fibrous ...Continue Reading

References

Jan 1, 1996·Cancer Genetics and Cytogenetics·S A VayegoM Varella-Garcia
Nov 12, 1998·Journal of Pediatric Orthopedics. Part B·F Lokiec, S Wientroub
Aug 22, 2000·The Journal of the American Academy of Orthopaedic Surgeons·R M Wilkins
Mar 17, 2001·Cancer Genetics and Cytogenetics·S A Vayego-Lourenco
Oct 24, 2002·Cancer Genetics and Cytogenetics·Kathleen E RichkindArmando Fraire
Oct 9, 2004·The Journal of Veterinary Medical Science·Murat SarierlerSerap Birincioglu
Mar 25, 2005·Cytopathology : Official Journal of the British Society for Clinical Cytology·U HandaS Bhardwaj
Sep 29, 2006·Southern Medical Journal·Rafath Baig, John L Eady
Jan 5, 2008·Archives of Orthopaedic and Trauma Surgery·Takahiro GotoNobuaki Funata
Apr 18, 2008·Diagnostic Cytopathology·Michael A HueningLeslie G Dodd
Aug 14, 2009·Veterinary Surgery : VS·Andrea I SpahniMichael H Stoffel
Aug 25, 2015·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·M PetazzoniB Beale

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Citations

Sep 4, 2020·BMC Veterinary Research·Michail VagiasRonan A Mullins

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