PMID: 9191693May 1, 1997Paper

Multimodal monitoring in patients with head injury: evaluation of the effects of treatment on cerebral oxygenation

The Journal of Trauma
A UnterbergW R Lanksch

Abstract

Recently, invasive intensive care unit monitoring of cerebral oxygenation has become feasible. The purpose of this study was to investigate the effects of standard therapeutic interventions used in the treatment of intracranial hypertension on cerebral oxygenation and other physiologic parameters in comatose patients. In the neurosurgical intensive care unit, Ptio2, and jugular bulb oxygen saturation (Sjvo2), arterial blood pressure, intracranial pressure (ICP), and cerebral perfusion pressure (CPP) were prospectively studied (0.1 Hz acquisition rate) with a multimodal monitoring system in 21 patients with severe traumatic brain injury during various treatment modalities: dopamine and mannitol infusion, head positioning, and induced arterial hypocapnia. For baseline CPP values below 40 mm Hg, dopamine infusion was more effective in decreasing ICP and improving Ptio2 and Sjvo2 than for initial CPP values above 60 mm Hg. Treatment with mannitol, although improving CPP and lowering ICP, did not affect Ptio2 and Sjvo2. CPP in this group, however, was always above 60 mm Hg. Forced hyperventilation to an end-tidal Pco2 of 21 mm Hg normalized ICP and CPP, but significantly reduced cerebral oxygenation. A CPP > 60 mm Hg emerges as the ...Continue Reading

References

Dec 1, 1978·Journal of the Neurological Sciences·D I GrahamD Doyle
Feb 1, 1992·Journal of Neurosurgery·M SheinbergR G Grossman
Mar 1, 1989·Journal of Neurology, Neurosurgery, and Psychiatry·D I GrahamD R McLellan
Nov 1, 1986·Journal of Neurosurgery·M J Rosner, I B Coley
Dec 1, 1995·Journal of Neurosurgery·M J RosnerA H Johnson
Feb 1, 1993·The Journal of Trauma·R M ChesnutM A Foulkes

❮ Previous
Next ❯

Citations

Sep 25, 1999·The Journal of Trauma·H MaxeinerM Brock
Jun 16, 1999·Clinical and Experimental Hypertension : CHE·E M GoldingR M Bryan
Jun 5, 1999·Anesthesia and Analgesia·D TalmorA A Artru
Jun 8, 2001·Critical Care Medicine·A S SarrafzadehA W Unterberg
Feb 21, 2002·Critical Care Nursing Quarterly·J R Yanko, K Mitcho
Mar 17, 2010·Critical Care Medicine·Gerard CurleyJohn G Laffey
Sep 12, 2014·Neurocritical Care·Mauro OddoUNKNOWN Participants in the International Multidisciplinary Consensus Conference on Multimodality Monitoring
Jun 30, 2015·Critical Care Medicine·Clotilde SchilteJean-François Payen
Jan 1, 2016·Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova·V I GorbachevE Yu Sedova
May 25, 2001·Current Opinion in Critical Care·M Alvarez del Castillo
Dec 17, 2002·Critical Care Medicine·Mark H Zornow, Donald S Prough
Oct 3, 2006·Current Opinion in Anaesthesiology·C Werner, E Kochs
Oct 3, 2006·Current Opinion in Anaesthesiology·S J Allen, C L Parmley
Jan 16, 2007·Neurosurgical Review·Erhard W LangNicholas W C Dorsch
May 24, 2012·Journal of Neurotrauma·Christopher BeynonOliver W Sakowitz
Mar 3, 2015·Annals of the New York Academy of Sciences·Halinder S Mangat, Roger Härtl
Jan 10, 2018·Military Medicine·Alexander PapangelouRomergryko G Geocadin
Jun 18, 2002·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Hayden White, Andrew Baker
Oct 13, 1998·Anesthesia and Analgesia·E A Bedell, D S Prough
Jan 6, 2005·The Neurologist·Michael A De Georgia, Anupa Deogaonkar
Oct 21, 2003·Current Neurology and Neuroscience Reports·Asita S SarrafzadehAndreas W Unterberg
Jan 27, 2012·Neurologia Medico-chirurgica·Minoru ShigemoriUNKNOWN Guidelines Committee on the Management of Severe Head Injury, Japan Society of Neurotraumatology
Nov 26, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Ursula K Rohlwink, Anthony A Figaji
Nov 3, 2009·Journal of Neurosurgery. Pediatrics·Anthony A FigajiJonathan C Peter
Feb 4, 2012·World Journal of Critical Care Medicine·John F Stover
Mar 1, 2019·Medical Sciences : Open Access Journal·Reto A Stocker
May 15, 2008·Cerebrovascular Diseases·UNKNOWN European Stroke Organisation (ESO) Executive Committee, UNKNOWN ESO Writing Committee
Mar 25, 2014·Intensive Care Medicine·Matthew A KirkmanMartin Smith
Aug 13, 2008·Neurocritical Care·Paul NyquistMarek A Mirski
Oct 19, 2002·Current Opinion in Critical Care·Iain K Haitsma, Andrew I R Maas
Nov 14, 1998·Journal of Neurotrauma·W A van den BrinkA I Maas
Aug 5, 2017·Frontiers in Neurology·Daniel Agustín GodoyFrancisco Murillo-Cabezas

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Related Papers

Tidsskrift for den Norske lægeforening : tidsskrift for praktisk medicin, ny række
Erik Waage NielsenRolf Salvesen
The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
J Kay
Journal of Trauma Nursing : the Official Journal of the Society of Trauma Nurses
J S WalkerE Siebelink
© 2021 Meta ULC. All rights reserved