Multimodal treatment and management strategies for intracranial hemangiopericytoma

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
Li-feng ChenDing-biao Zhou

Abstract

Intracranial hemangiopericytoma (HPC) is a rare malignant meningothelial tumor. The authors retrospectively reviewed the long-term clinical outcomes of patients with HPC with regard to treatment modalities and histopathological grades. Eighteen women and 20 men (mean age 38.5 years, range, 18-62 years) were observed over an average follow-up period of 61 months (range, 15-133 months) between 2003 and 2013. The initial treatment modalities included total tumor resection followed by conventional radiotherapy (RT) (n=27), and subtotal tumor resection followed by stereotactic radiosurgery (n=11). One patient (3%) had permanent neurological deficits, and six patients (16%) died. Thirteen patients (34%) suffered recurrence. One year, 5 year, and 10 year recurrence-free survival rates were 100%, 70%, and 39%, respectively. Five patients (13%) developed metastasis. One year, 5 year, and 10 year metastasis-free survival rates were 100%, 89%, 74%, respectively. Low grade tumors were associated with longer overall survival, recurrence-free interval and metastasis-free interval (log-rank, p<0.05). Radical resection with RT was associated with longer overall survival and recurrence-free interval (log-rank, p<0.05), but had no effect on the ...Continue Reading

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Citations

Sep 1, 2015·International Journal of Surgery Case Reports·Terry P NickersonJuliane Bingener
Feb 3, 2016·World Neurosurgery·James E TownerYan Michael Li
Feb 11, 2018·Journal of Neuro-oncology·Connor J KinslowTony J C Wang
Oct 15, 2019·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Or Cohen-Inbar
Apr 3, 2020·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Lianwang LiDabiao Zhou
Jun 1, 2020·Neurocirugía·Francisco Marcó Del PontAndrés Cervio

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