Abstract
Intracranial hemangiopericytoma (HPC) is a rare malignant meningothelial tumor. The authors retrospectively reviewed the long-term clinical outcomes of patients with HPC with regard to treatment modalities and histopathological grades. Eighteen women and 20 men (mean age 38.5 years, range, 18-62 years) were observed over an average follow-up period of 61 months (range, 15-133 months) between 2003 and 2013. The initial treatment modalities included total tumor resection followed by conventional radiotherapy (RT) (n=27), and subtotal tumor resection followed by stereotactic radiosurgery (n=11). One patient (3%) had permanent neurological deficits, and six patients (16%) died. Thirteen patients (34%) suffered recurrence. One year, 5 year, and 10 year recurrence-free survival rates were 100%, 70%, and 39%, respectively. Five patients (13%) developed metastasis. One year, 5 year, and 10 year metastasis-free survival rates were 100%, 89%, 74%, respectively. Low grade tumors were associated with longer overall survival, recurrence-free interval and metastasis-free interval (log-rank, p<0.05). Radical resection with RT was associated with longer overall survival and recurrence-free interval (log-rank, p<0.05), but had no effect on the ...Continue Reading
References
Oct 1, 1989·Neurosurgery·B L GuthrieE G Shaw
Mar 1, 1985·Surgical Neurology·J JääskeläinenS Valtonen
Apr 27, 2001·Neurosurgery·H DufourF Grisoli
Jun 21, 2003·Journal of Neurosurgery·Robert D EckerJan C Buckner
Mar 26, 2004·Cancer·Serdar SoyuerMoshe H Maor
Oct 14, 2005·Cancer·Stephanie E CombsDaniela Schulz-Ertner
Jul 10, 2007·Acta Neuropathologica·David N LouisPaul Kleihues
Aug 1, 2007·Zentralblatt für Neurochirurgie·H BassiouniD Stolke
Dec 29, 2009·Clinical Neurology and Neurosurgery·Prakash M ShettyEpari Sridhar
Apr 7, 2010·Journal of Neurosurgery·Martin J RutkowskiAndrew T Parsa
Aug 3, 2010·Journal of Neurosurgery·Marco SchiaritiNeil Kitchen
Aug 13, 2011·Cancer·Martin J RutkowskiAndrew T Parsa
Jul 14, 2012·Acta neurochirurgica·Narendra KumarSuresh Chander Sharma
Nov 15, 2012·Neurosurgery·Amol J GhiaPaul D Brown
Jul 11, 2013·Neurosurgery·Amol J GhiaPaul D Brown
Citations
Sep 1, 2015·International Journal of Surgery Case Reports·Terry P NickersonJuliane Bingener
Feb 3, 2016·World Neurosurgery·James E TownerYan Michael Li
Feb 11, 2018·Journal of Neuro-oncology·Connor J KinslowTony J C Wang
Jan 27, 2018·Journal of Neurosurgery·Byung Sup KimHo Jun Seol
Nov 21, 2019·Neurology India·Amandeep KumarShashank S Kale
Oct 15, 2019·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Or Cohen-Inbar
Mar 20, 2018·Journal of Neuro-oncology·Tarini RatneswarenKeyoumars Ashkan
Jul 12, 2017·Journal of Neuro-oncology·Charles ChampeauxLaurence Dunn
Apr 3, 2020·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Lianwang LiDabiao Zhou
Sep 19, 2019·Surgical Neurology International·Sumanth ReddyToral R Patel
Apr 28, 2017·Journal of Neuro-oncology·Connor J KinslowTony J C Wang
Nov 6, 2020·International Journal of General Medicine·Zhixiang SunZhiquan Jiang
Jun 1, 2020·Neurocirugía·Francisco Marcó Del PontAndrés Cervio
Jun 12, 2020·World Neurosurgery·Masahiro OishiYoshio Nakajima
Aug 14, 2021·Clinical Neurology and Neurosurgery·Subhas KonarB Indira Devi