Multimodality approach of perioperative 18F-FDG PET/CT imaging, intraoperative 18F-FDG handheld gamma probe detection, and intraoperative ultrasound for tumor localization and verification of resection of all sites of hypermetabolic activity in a case of occult recurrent metastatic melanoma

World Journal of Surgical Oncology
Stephen P PovoskiMichael J Walker

Abstract

The use of diagnostic 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) imaging for the staging, restaging, and treatment monitoring of melanoma patients has become a well-recognized standard of care. It plays a key role in detecting sites of occult disease and is widely utilized in the medical and surgical planning of such patients. In the current report, we describe an innovative multimodality approach of perioperative 18F-FDG PET/CT imaging, intraoperative 18F-FDG handheld gamma probe detection, and intraoperative ultrasound for tumor localization and verification of resection of all sites of hypermetabolic tumor foci in a case of occult recurrent metastatic melanoma. This report discusses a case of occult recurrent metastatic melanoma, isolated to three separate sites within the subcutaneous tissues of the left thigh region, which was not clinically apparent but was found on diagnostic restaging whole body 18F-FDG PET/CT scan utilizing an intravenous injection of 14.8 mCi 18F-FDG. Then, on the day of surgery, the patient received an intravenous injection of 12.8 mCi 18F-FDG. A multimodality approach of intraoperative handheld gamma probe detection, intraoperative ultrasound tumor loc...Continue Reading

References

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Citations

Jul 12, 2008·European Journal of Nuclear Medicine and Molecular Imaging·Stephen P PovoskiMichael V Knopp
Oct 21, 2009·Current Oncology Reports·Rebecca A Brooks, Matthew A Powell
Jun 1, 2009·Therapeutic Advances in Urology·Eamonn E BahnsonRobert R Bahnson
Jan 29, 2009·World Journal of Surgical Oncology·Stephen P PovoskiEdward W Martin
Apr 24, 2010·Radiology·Nathan C HallMichael V Knopp
Oct 13, 2009·Revista española de medicina nuclear·I Hervás BenitoA Mateo Navarro
May 22, 2010·Journal of Cutaneous Medicine and Surgery·Brenda A ShooStanley P L Leong
May 22, 2009·AJR. American Journal of Roentgenology·Baris TurkbeyPeter L Choyke
Jun 30, 2010·Expert Review of Medical Devices·Edward W MartinStephen P Povoski
Mar 14, 2013·Expert Review of Medical Devices·Nathan C HallEdward W Martin
Apr 26, 2017·Current Treatment Options in Oncology·Javier Martínez TruferoRoberto Pazo Cid

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Methods Mentioned

BETA
surgical resection
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